NCT00196742 · Observational
Fabry Disease Registry & Pregnancy Sub-registry
Fabry Disease
Study overall: Recruiting · source record updated 23 June 2026.
7 England locations · 7 explicitly recorded as recruiting.
RESEARCH IN ENGLAND
Explore clinical trials with England locations
Search 2,970 registered studies with identifiable England locations in our dated ClinicalTrials.gov snapshot. Explore the study and local recruitment details before contacting the research team.
59 matching studies · ordered by study identifier.
The area filter uses exact source postcodes. Locations without a matched postcode remain in the England-wide results.
NCT00231400 · Observational
Pompe Disease Registry Protocol
Glycogen Storage Disease Type II · Pompe Disease
Study overall: Recruiting · source record updated 23 June 2026.
9 England locations · 9 explicitly recorded as recruiting.
NCT00358943 · Observational
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry
Gaucher Disease · Cerebroside Lipidosis Syndrome · Glucocerebrosidase Deficiency Disease · Glucosylceramide Beta-Glucosidase Deficiency Disease
Study overall: Recruiting · source record updated 14 April 2026.
8 England locations · 8 explicitly recorded as recruiting.
NCT01633489 · Observational
Lysosomal Acid Lipase (LAL) Deficiency Registry
Lysosomal Acid Lipase Deficiency · Cholesterol Ester Storage Disease · Wolman Disease · Acid Cholesteryl Ester Hydrolase Deficiency, Type 2 · Acid Lipase Deficiency · LIPA Deficiency · LAL-Deficiency
Study overall: Recruiting · source record updated 6 March 2026.
5 England locations · 5 explicitly recorded as recruiting.
NCT02735707 · Interventional
Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia
Community-acquired Pneumonia, Influenza, COVID-19
Study overall: Recruiting · source record updated 12 July 2024.
131 England locations · 54 explicitly recorded as recruiting.
NCT04165486 · Interventional
Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ION464 Administered to Adults With Multiple System Atrophy (HORIZON)
Multiple System Atrophy
Study overall: Recruiting · source record updated 27 April 2026.
4 England locations · 4 explicitly recorded as recruiting.
NCT04274283 · Observational
Tessa Jowell BRAIN MATRIX - Platform Study
Glioma
Study overall: Recruiting · source record updated 5 May 2026.
11 England locations · 10 explicitly recorded as recruiting.
NCT04775706 · Interventional
Phase 2 Study to Assess the Safety, PK, and PD of Sonefpeglutide (HM15912) in SBS-IF Subjects
Short Bowel Syndrome
Study overall: Recruiting · source record updated 12 August 2026.
2 England locations · 2 explicitly recorded as recruiting.
NCT04939935 · Interventional
Implementation of Metformin theraPy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD)
Autosomal Dominant Polycystic Kidney Disease
Study overall: Recruiting · source record updated 31 March 2026.
25 England locations · 15 explicitly recorded as recruiting.
NCT05444465 · Interventional
Use of the REGENETEN™ Bioinductive Implant System in High Grade Partial-thickness Tears
Rotator Cuff Injuries
Study overall: Recruiting · source record updated 5 August 2026.
4 England locations · 3 explicitly recorded as recruiting.
NCT05476913 · Interventional
GEKO Venous Thromboembolism Prevention Study
Stroke, Acute · Venous Thromboembolism · Deep Vein Thrombosis · Pulmonary Embolism
Study overall: Recruiting · source record updated 4 March 2025.
18 England locations · 17 explicitly recorded as recruiting.
NCT05481879 · Interventional
Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-101 in Participants With Myotonic Dystrophy Type 1
Myotonic Dystrophy Type 1 (DM1)
Study overall: Recruiting · source record updated 12 May 2026.
3 England locations · 3 explicitly recorded as recruiting.
NCT05485961 · Interventional
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
End Stage Kidney Disease
Study overall: Recruiting · source record updated 11 August 2026.
14 England locations · 12 explicitly recorded as recruiting.
NCT05658497 · Observational
Pregnancy Exposure Registry for Vumerity (Diroximel Fumarate)
Multiple Sclerosis
Study overall: Recruiting · source record updated 11 August 2026.
1 England locations · 1 explicitly recorded as recruiting.
NCT05667142 · Interventional
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
Primary Generalized Tonic-Clonic Seizures
Study overall: Recruiting · source record updated 10 August 2026.
5 England locations · 5 explicitly recorded as recruiting.
NCT05712200 · Interventional
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)
Atrial Fibrillation (AF)
Study overall: Recruiting · source record updated 13 July 2026.
26 England locations · 22 explicitly recorded as recruiting.
NCT05755386 · Interventional
Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGN
IC-MPGN
Study overall: Recruiting · source record updated 13 July 2026.
4 England locations · 4 explicitly recorded as recruiting.
NCT05789758 · Observational
A Study to Learn How Nusinersen (Spinraza) Affects Participants With Spinal Muscular Atrophy (SMA) Who Took it Before or During Pregnancy And About The Health of Their Babies
Muscular Atrophy, Spinal
Study overall: Recruiting · source record updated 9 March 2026.
10 England locations · 10 explicitly recorded as recruiting.
NCT05895786 · Interventional
A Study to Understand How the Study Medicine (PF-06823859) Works in People With Active Idiopathic Inflammatory Myopathies [Dermatomyositis (DM) and Polymyositis (PM)]
Myositis
Study overall: Recruiting · source record updated 1 June 2026.
2 England locations · 2 explicitly recorded as recruiting.
NCT05980949 · Interventional
Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)
Psychosis Associated With Alzheimer's Disease
Study overall: Recruiting · source record updated 6 July 2026.
7 England locations · 0 explicitly recorded as recruiting.
More ways to explore research
This is a selected international registry feed, not every study taking place in England. NIHR also lists participation opportunities, including studies that may not appear in this selection.
Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).
Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.
How we selected and connected these records
Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.