NCT04939935
Implementation of Metformin theraPy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD)
Registered research study with 25 identifiable England locations. See source dates, location-specific recruitment and the original study record.
Study facts
- Conditions recorded
- Autosomal Dominant Polycystic Kidney Disease
- Lead sponsor
- The University of Queensland
- Study type
- Interventional
- Overall status
- Recruiting · this can differ by location
- Age range in the record
- 18 Years to 70 Years
- Sex eligibility field
- All
- Healthy volunteers accepted
- No, according to the record
- Phase
- Phase3
- Study record last updated
- 31 March 2026
- Study team last verified status
- 2026-03
These fields are a starting point. Eligibility can include diagnosis, treatment history and other criteria shown only in the complete source record. A registry entry does not establish treatment effectiveness.
England study locations
A location is reproduced as named in the study record. A source map point can represent a town; it is not used here as a hospital entrance or to identify a care provider.
| Location in the source | Local recruitment status | Geographic connection |
|---|---|---|
| Royal Devon & Exeter Hospital Exeter · EX2 5DW | Recruiting | Care in Exeter England postcode |
| Nottingham Renal Unit, Nottingham City Hospital Nottingham · NG5 1PB | Not yet recruiting | Care in Nottingham England postcode |
| Royal Preston Hospital Preston · PR2 9HT | Not yet recruiting | Care in Preston England postcode |
| Salford Royal Hospital Salford · M6 8HD | Recruiting | Care in Salford England postcode |
| Leicester General Hospital Leicester · LE5 4PW | Recruiting | Care in Leicester England postcode |
| St Helier Hospital Carshalton · SM5 1AA | Not yet recruiting | Care in Sutton England postcode |
| Aintree University Hospital Liverpool · L9 7AL | Recruiting | Care in Liverpool England postcode |
| Norfolk and Norwich University Hospital Norwich · NR4 7UY | Not yet recruiting | Care in South Norfolk England postcode |
| Oxford Kidney Unit, Churchill Hospital, Oxford · OX3 7LE | Recruiting | Care in Oxford England postcode |
| Doncaster Royal Infirmary Doncaster · DN2 5LT | Recruiting | Care in Doncaster England postcode |
| Sheffield Kidney Institute Sheffield · S5 7AU | Recruiting | Care in Sheffield England postcode |
| Royal Stoke University Hospital Stoke-on-Trent · ST4 6QG | Not yet recruiting | Care in Stoke-on-Trent England postcode |
| Freeman Hospital Newcastle upon Tyne · NE7 7DN | Not yet recruiting | Care in Newcastle upon Tyne England postcode |
| Queen Elizabeth Hospital Birmingham Birmingham · B15 2GW | Not yet recruiting | Care in Birmingham England postcode |
| Bradford Renal Unit, St Luke's Hospital Bradford · BD5 0NA | Recruiting | Care in Bradford England postcode |
| Epsom and St Helier University Hospitals Carshalton | Recruiting | England location Source location point within ONS England boundary |
| The Royal London Hospital London · E1 1FR | Not yet recruiting | Care in Tower Hamlets England postcode |
| Royal Free Hospital London · NW3 2QG | Not yet recruiting | Care in Camden England postcode |
| King's College Hospital London · SE5 9RS | Not yet recruiting | Care in Lambeth England postcode |
| St George's University Hospital London | Recruiting | England location Source location point within ONS England boundary |
| Nottingham University Hospital Nottingham | Recruiting | England location Source location point within ONS England boundary |
| University Hospitals Plymouth NHS Trust Plymouth | Recruiting | England location Source location point within ONS England boundary |
| East & North Hertfordshire Teaching NHS Trust Stevenage | Recruiting | England location Source location point within ONS England boundary |
| South Tyneside and Sunderland NHS Foundation Trust Sunderland | Recruiting | England location Source location point within ONS England boundary |
| York and Scarborough Teacehing Hospitals York | Recruiting | England location Source location point within ONS England boundary |
Questions for the research team
- Is this exact location currently enrolling participants, and do my circumstances meet the full criteria?
- What visits, tests, possible risks and follow-up would participation involve?
- Are travel costs or accessibility arrangements available?
- How would participation affect my usual care, and what happens if I withdraw?
Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).
Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.
How we selected and connected these records
Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.