RESEARCH IN ENGLAND

Explore clinical trials with England locations

Search 2,970 registered studies with identifiable England locations in our dated ClinicalTrials.gov snapshot. Explore the study and local recruitment details before contacting the research team.

Condition, study or locationRecorded care areaStatus at an England locationClear filters

18 matching studies · ordered by study identifier.

The area filter uses exact source postcodes. Locations without a matched postcode remain in the England-wide results.

NCT02735707 · Interventional

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

Community-acquired Pneumonia, Influenza, COVID-19

Study overall: Recruiting · source record updated 12 July 2024.

131 England locations · 54 explicitly recorded as recruiting.

NCT04050345 · Observational

Tracking Mutations in Cell Free Tumour DNA to Predict Relapse in Early Colorectal Cancer

Colorectal Cancer

Study overall: Recruiting · source record updated 14 June 2024.

62 England locations · 57 explicitly recorded as recruiting.

NCT04109079 · Interventional

Axillary Management in Breast Cancer Patients With Needle Biopsy Proven Nodal Metastases After Neoadjuvant Chemotherapy

Breast Cancer · Sentinel Lymph Node · Neoplasm, Breast

Study overall: Recruiting · source record updated 30 March 2026.

80 England locations · 78 explicitly recorded as recruiting.

NCT05476913 · Interventional

GEKO Venous Thromboembolism Prevention Study

Stroke, Acute · Venous Thromboembolism · Deep Vein Thrombosis · Pulmonary Embolism

Study overall: Recruiting · source record updated 4 March 2025.

18 England locations · 17 explicitly recorded as recruiting.

NCT05696626 · Interventional

Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

Metastatic Breast Cancer

Study overall: Recruiting · source record updated 22 June 2026.

8 England locations · 7 explicitly recorded as recruiting.

NCT06152575 · Interventional

MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)

Multiple Myeloma

Study overall: Recruiting · source record updated 24 August 2026.

16 England locations · 16 explicitly recorded as recruiting.

NCT06345729 · Interventional

A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)

Non-small Cell Lung Cancer

Study overall: Recruiting · source record updated 8 September 2026.

2 England locations · 2 explicitly recorded as recruiting.

NCT06641466 · Interventional

A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual Migraine

Menstrual Migraine

Study overall: Recruiting · source record updated 9 July 2026.

7 England locations · 7 explicitly recorded as recruiting.

NCT06830759 · Observational

Real-World Study to Assess Subcutaneous Epcoritamab in Adult Participants With Diffuse Large B-Cell and Follicular Lymphoma

Diffuse Large B-cell Lymphoma · Follicular Lymphoma

Study overall: Recruiting · source record updated 17 February 2026.

7 England locations · 7 explicitly recorded as recruiting.

NCT06980480 · Interventional

A Study of Gammagard Liquid (Immune Globulin Infusion, 10%) to Prevent Infections in Adults With Multiple Myeloma

Multiple Myeloma · Secondary Immunodeficiency

Study overall: Recruiting · source record updated 9 September 2026.

5 England locations · 5 explicitly recorded as recruiting.

NCT06984627 · Interventional

A Study to Investigate the Efficacy and Safety of Rilzabrutinib in Adult Participants With Graves' Disease

Graves' Disease

Study overall: Recruiting · source record updated 7 July 2026.

2 England locations · 2 explicitly recorded as recruiting.

NCT07000357 · Interventional

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

Cardiovascular Disease

Study overall: Recruiting · source record updated 24 August 2026.

31 England locations · 31 explicitly recorded as recruiting.

NCT07067658 · Interventional

Monitoring Oedema in Heart Failure to Improve Function and Reduce Hospitalisation Risk

Heart Failure

Study overall: Recruiting · source record updated 28 July 2026.

14 England locations · 12 explicitly recorded as recruiting.

NCT07181109 · Interventional

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

High Risk Cardiovascular Disease · Hypertension · High Cardiovascular Risk

Study overall: Recruiting · source record updated 19 August 2026.

44 England locations · 40 explicitly recorded as recruiting.

NCT07229027 · Observational

Global Overweight and oBesE (GLOBE) Patient Registry, Development and Implementation of Disease-specific: Severity, Quality of Life and Cost Instruments.

Overweight (BMI > 25) · Obesity & Overweight

Study overall: Recruiting · source record updated 14 November 2025.

1 England locations · 1 explicitly recorded as recruiting.

NCT07420283 · Interventional

A Study of Brenipatide in Participants With Opioid Use Disorder

Opioid Use Disorder

Study overall: Recruiting · source record updated 4 September 2026.

11 England locations · 6 explicitly recorded as recruiting.

NCT07610395 · Interventional

Trial Comparing the Safety and Efficacy of Two Different Oral VPV Doses With Placebo as Treatment for RV in Participants With COPD

Rhinovirus Infection

Study overall: Recruiting · source record updated 10 September 2026.

6 England locations · 6 explicitly recorded as recruiting.

NCT07740369 · Observational

An Exploration of Family Centred Care (FCC) in UK Inpatient Wards

Nursing · Family Centered Care · Ethics Nursing · Family Nursing

Study overall: Recruiting · source record updated 31 July 2026.

1 England locations · 1 explicitly recorded as recruiting.

More ways to explore research

This is a selected international registry feed, not every study taking place in England. NIHR also lists participation opportunities, including studies that may not appear in this selection.

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Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).

Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.

How we selected and connected these records

Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.