NCT06265727 · Interventional
A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors
Solid Tumor, Adult
Study overall: Recruiting · source record updated 8 January 2026.
8 England locations · 8 explicitly recorded as recruiting.
RESEARCH IN ENGLAND
Explore clinical trials with England locations
Search 2,970 registered studies with identifiable England locations in our dated ClinicalTrials.gov snapshot. Explore the study and local recruitment details before contacting the research team.
212 matching studies · ordered by study identifier.
The area filter uses exact source postcodes. Locations without a matched postcode remain in the England-wide results.
NCT06268340 · Interventional
Hearing and Structure Preservation Via ECochG
Hearing Loss, Sensorineural · Severe-to-profound Hearing Loss
Study overall: Recruiting · source record updated 6 January 2026.
1 England locations · 1 explicitly recorded as recruiting.
NCT06307652 · Interventional
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
Heart Failure and Impaired Kidney Function
Study overall: Recruiting · source record updated 26 June 2026.
16 England locations · 10 explicitly recorded as recruiting.
NCT06308978 · Interventional
A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease
Antineutrophilic Cytoplasmic Antibody (ANCA)- Associated Vasculitis (AAV) · Idiopathic Inflammatory Myositis (IIM) · Systemic Sclerosis (SSc) · Systemic Lupus Erythematosus (SLE) · Lupus Nephritis
Study overall: Recruiting · source record updated 22 May 2026.
3 England locations · 3 explicitly recorded as recruiting.
NCT06336317 · Interventional
Effect of infLuenza vaccInation After Myocardial INfArction on Cardiac inflammaTory responsE
Acute Myocardial Infarction · Cardiovascular Diseases · Inflammatory Response
Study overall: Recruiting · source record updated 7 April 2026.
1 England locations · 1 explicitly recorded as recruiting.
NCT06340568 · Interventional
A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer
Endometrial Cancer
Study overall: Recruiting · source record updated 1 September 2026.
11 England locations · 11 explicitly recorded as recruiting.
NCT06379789 · Interventional
A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia B
Hemophilia B
Study overall: Recruiting · source record updated 5 August 2026.
6 England locations · 6 explicitly recorded as recruiting.
NCT06385080 · Interventional
A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer
Squamous Cell Carcinoma of Head and Neck
Study overall: Recruiting · source record updated 28 August 2026.
7 England locations · 6 explicitly recorded as recruiting.
NCT06386185 · Observational
Developing the Probability Algorithm for Pulmonary Hypertension Echocardiography
Pulmonary Hypertension
Study overall: Recruiting · source record updated 18 June 2025.
4 England locations · 1 explicitly recorded as recruiting.
NCT06417814 · Interventional
A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Metastatic Non-small Cell Lung Cancer
Study overall: Recruiting · source record updated 14 May 2026.
6 England locations · 6 explicitly recorded as recruiting.
NCT06427694 · Observational
Low-Dose IL-2 For The Reduction Of Vascular Inflammation In ACS -Clinical Outcomes & Follow-up Study
Acute Coronary Syndromes
Study overall: Recruiting · source record updated 10 June 2024.
1 England locations · 1 explicitly recorded as recruiting.
NCT06431594 · Interventional
A Study to Evaluate the Safety,Tolerability, Pharmacokinetics and Clinical Activity of Mocertatug Rezetecan for Injection in Participants With Advanced Solid Tumors (BEHOLD-1)
Solid Tumors · Neoplasms
Study overall: Recruiting · source record updated 25 June 2026.
3 England locations · 3 explicitly recorded as recruiting.
NCT06435156 · Interventional
Sotagliflozin in Patients With Heart Failure Symptoms and Type 1 Diabetes
Type 1 Diabetes · Heart Failure
Study overall: Recruiting · source record updated 6 April 2026.
12 England locations · 12 explicitly recorded as recruiting.
NCT06439277 · Interventional
A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)
Obesity · Weight Gain
Study overall: Recruiting · source record updated 4 September 2026.
8 England locations · 0 explicitly recorded as recruiting.
NCT06479135 · Interventional
Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib
Myelofibrosis · Post-PV MF · Post-ET Myelofibrosis · Primary Myelofibrosis · MF
Study overall: Recruiting · source record updated 25 September 2025.
12 England locations · 12 explicitly recorded as recruiting.
NCT06499285 · Interventional
A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions
Myelodysplastic Syndromes
Study overall: Recruiting · source record updated 21 August 2026.
11 England locations · 9 explicitly recorded as recruiting.
NCT06505798 · Interventional
Cryoballoon/Radiofrequency/Pulsed Field Ablation of Atrial Fibrillation Versus Medical Treatment for Heart
Atrial Fibrillation (AF)
Study overall: Recruiting · source record updated 4 May 2026.
20 England locations · 20 explicitly recorded as recruiting.
NCT06507579 · Observational
Hydra Registry - UK
Aortic Valve Stenosis
Study overall: Recruiting · source record updated 18 August 2026.
3 England locations · 2 explicitly recorded as recruiting.
NCT06525220 · Interventional
A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR - HN1)
Head and Neck Squamous Cell Carcinoma
Study overall: Recruiting · source record updated 2 June 2026.
10 England locations · 10 explicitly recorded as recruiting.
NCT06534190 · Interventional
CD8 PET Imaging in Metastatic Solid Tumours
Locally Advanced Solid Tumor
Study overall: Recruiting · source record updated 9 February 2026.
1 England locations · 0 explicitly recorded as recruiting.
More ways to explore research
This is a selected international registry feed, not every study taking place in England. NIHR also lists participation opportunities, including studies that may not appear in this selection.
Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).
Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.
How we selected and connected these records
Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.