NCT06525220
A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR - HN1)
Registered research study with 10 identifiable England locations. See source dates, location-specific recruitment and the original study record.
Study facts
- Conditions recorded
- Head and Neck Squamous Cell Carcinoma
- Lead sponsor
- Merus B.V.
- Study type
- Interventional
- Overall status
- Recruiting · this can differ by location
- Age range in the record
- 18 Years to Not specified
- Sex eligibility field
- All
- Healthy volunteers accepted
- No, according to the record
- Phase
- Phase3
- Study record last updated
- 2 June 2026
- Study team last verified status
- 2026-04
These fields are a starting point. Eligibility can include diagnosis, treatment history and other criteria shown only in the complete source record. A registry entry does not establish treatment effectiveness.
England study locations
A location is reproduced as named in the study record. A source map point can represent a town; it is not used here as a hospital entrance or to identify a care provider.
| Location in the source | Local recruitment status | Geographic connection |
|---|---|---|
| Site 102 Cambridge · CB20QQ | Recruiting | Care in Cambridge England postcode |
| Site 132 London · EC1A 7BE | Recruiting | Care in City of London England postcode |
| Site 90 London · SE19RT | Recruiting | Care in Southwark England postcode |
| Site 69 London · SW3 6JJ | Recruiting | Care in Kensington and Chelsea England postcode |
| Site 173 Manchester · M20 4BX | Recruiting | Care in Manchester England postcode |
| Site 177 Newcastle upon Tyne · NE7 7DN | Recruiting | Care in Newcastle upon Tyne England postcode |
| Site 83 Northwood · HA62RN | Recruiting | Care in Hillingdon England postcode |
| Site 147 Southampton · SO16 6YD | Recruiting | Care in Southampton England postcode |
| Site 70 Sutton · SM2 5PT | Recruiting | Care in Sutton England postcode |
| Site 135 Taunton · TA1 5DA | Recruiting | Care in Somerset England postcode |
Questions for the research team
- Is this exact location currently enrolling participants, and do my circumstances meet the full criteria?
- What visits, tests, possible risks and follow-up would participation involve?
- Are travel costs or accessibility arrangements available?
- How would participation affect my usual care, and what happens if I withdraw?
Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).
Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.
How we selected and connected these records
Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.