RESEARCH IN ENGLAND

Explore clinical trials with England locations

Search 2,970 registered studies with identifiable England locations in our dated ClinicalTrials.gov snapshot. Explore the study and local recruitment details before contacting the research team.

Condition, study or locationRecorded care areaStatus at an England locationClear filters

266 matching studies · ordered by study identifier.

The area filter uses exact source postcodes. Locations without a matched postcode remain in the England-wide results.

NCT04804553 · Interventional

Apremilast Pediatric Study in Children With Active Juvenile Psoriatic Arthritis

Active Juvenile Psoriatic Arthritis

Study overall: Recruiting · source record updated 3 September 2026.

4 England locations · 2 explicitly recorded as recruiting.

NCT04888741 · Interventional

Methods of T Cell Depletion Trial (MoTD)

Acute Myeloid Leukemia · Acute Lymphoblastic Leukemia · Chronic Myelomonocytic Leukemia · Myelodysplastic Syndromes · Non Hodgkin Lymphoma · Hodgkin Lymphoma · Multiple Myeloma · Chronic Myelogenous Leukemia · Myelofibrosis

Study overall: Recruiting · source record updated 5 May 2026.

15 England locations · 15 explicitly recorded as recruiting.

NCT04928846 · Interventional

A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer

Study overall: Recruiting · source record updated 9 September 2026.

6 England locations · 6 explicitly recorded as recruiting.

NCT04939935 · Interventional

Implementation of Metformin theraPy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD)

Autosomal Dominant Polycystic Kidney Disease

Study overall: Recruiting · source record updated 31 March 2026.

25 England locations · 15 explicitly recorded as recruiting.

NCT04965298 · Interventional

Treating People With Idiopathic Pulmonary Fibrosis With the Addition of Lansoprazole

Idiopathic Pulmonary Fibrosis

Study overall: Recruiting · source record updated 22 December 2025.

50 England locations · 36 explicitly recorded as recruiting.

NCT05002543 · Observational

CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting

Cardiac Valve Disease

Study overall: Recruiting · source record updated 6 March 2024.

3 England locations · 3 explicitly recorded as recruiting.

NCT05076175 · Interventional

A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

Colitis, Ulcerative

Study overall: Recruiting · source record updated 23 July 2026.

4 England locations · 3 explicitly recorded as recruiting.

NCT05102019 · Interventional

Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II

Refractory Angina

Study overall: Recruiting · source record updated 26 August 2026.

20 England locations · 20 explicitly recorded as recruiting.

NCT05130437 · Interventional

A Study to Assess the Long-term Safety and Clinical Activity of mRNA-3927 in Participants Previously Enrolled in the mRNA-3927-P101 Study

Propionic Acidemia

Study overall: Recruiting · source record updated 23 March 2026.

4 England locations · 3 explicitly recorded as recruiting.

NCT05183646 · Interventional

A Study of the Efficacy and Safety of DMX-200 in Patients With FSGS Who Are Receiving an ARB

FSGS

Study overall: Recruiting · source record updated 3 February 2026.

15 England locations · 4 explicitly recorded as recruiting.

NCT05295433 · Interventional

An Extension Study to Evaluate the Long-Term Safety and Clinical Activity of mRNA-3705 in Participants Previously Enrolled in Other Clinical Studies of mRNA-3705

Methylmalonic Acidemia

Study overall: Recruiting · source record updated 23 December 2025.

2 England locations · 1 explicitly recorded as recruiting.

NCT05319353 · Interventional

A Study to Evaluate the Safety and Tolerability, Pharmacokinetics, and Antiviral Activity of Maribavir for the Treatment of Cytomegalovirus (CMV) Infection in Children and Adolescents Who Have Received a Hematopoietic Stem Cell Transplant (HSCT) or a Solid Organ Transplant (SOT)

Cytomegalovirus (CMV)

Study overall: Recruiting · source record updated 22 May 2026.

5 England locations · 5 explicitly recorded as recruiting.

NCT05327114 · Interventional

Efficacy and Safety Study of Nipocalimab for Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

Study overall: Recruiting · source record updated 28 August 2026.

4 England locations · 3 explicitly recorded as recruiting.

NCT05429632 · Interventional

Mocravimod as Adjunctive and Maintenance Treatment in AML Patients Undergoing Allo-HCT

Adult Acute Myeloid Leukemia

Study overall: Recruiting · source record updated 17 July 2026.

8 England locations · 6 explicitly recorded as recruiting.

NCT05441839 · Observational

UK Heart Failure With Preserved Ejection Fraction

Heart Failure With Preserved Ejection Fraction (HFpEF)

Study overall: Recruiting · source record updated 6 May 2025.

22 England locations · 22 explicitly recorded as recruiting.

NCT05442567 · Interventional

A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

Ulcerative Colitis · Crohn's Disease

Study overall: Recruiting · source record updated 7 May 2026.

5 England locations · 1 explicitly recorded as recruiting.

NCT05476913 · Interventional

GEKO Venous Thromboembolism Prevention Study

Stroke, Acute · Venous Thromboembolism · Deep Vein Thrombosis · Pulmonary Embolism

Study overall: Recruiting · source record updated 4 March 2025.

18 England locations · 17 explicitly recorded as recruiting.

NCT05485961 · Interventional

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)

End Stage Kidney Disease

Study overall: Recruiting · source record updated 11 August 2026.

14 England locations · 12 explicitly recorded as recruiting.

NCT05489705 · Observational

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

Obstructive Hypertrophic Cardiomyopathy

Study overall: Recruiting · source record updated 19 August 2026.

6 England locations · 4 explicitly recorded as recruiting.

NCT05533697 · Interventional

Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors

Advanced Solid Tumors

Study overall: Recruiting · source record updated 14 July 2026.

8 England locations · 8 explicitly recorded as recruiting.

More ways to explore research

This is a selected international registry feed, not every study taking place in England. NIHR also lists participation opportunities, including studies that may not appear in this selection.

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Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).

Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.

How we selected and connected these records

Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.