RESEARCH IN ENGLAND

Explore clinical trials with England locations

Search 2,970 registered studies with identifiable England locations in our dated ClinicalTrials.gov snapshot. Explore the study and local recruitment details before contacting the research team.

Condition, study or locationRecorded care areaStatus at an England locationClear filters

142 matching studies · ordered by study identifier.

The area filter uses exact source postcodes. Locations without a matched postcode remain in the England-wide results.

NCT06524830 · Interventional

A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

Treatment Resistant Depression

Study overall: Recruiting · source record updated 11 May 2026.

4 England locations · 4 explicitly recorded as recruiting.

NCT06541704 · Interventional

A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy

Age-related Macular Degeneration (AMD) · Geographic Atrophy (GA)

Study overall: Recruiting · source record updated 25 August 2026.

6 England locations · 6 explicitly recorded as recruiting.

NCT06545331 · Interventional

Study of XB010 in Subjects With Solid Tumors

Locally Advanced or Metastatic Solid Tumors · Esophageal Squamous Cell Cancer · Head and Neck Squamous Cell Cancer · NSCLC (Non-small Cell Lung Cancer) · Hormone-receptor-positive Breast Cancer · Triple Negative Breast Cancer (TNBC)

Study overall: Recruiting · source record updated 22 June 2026.

4 England locations · 4 explicitly recorded as recruiting.

NCT06551142 · Interventional

A Study of GSK5764227 in Participants With Advanced Solid Tumors (EMBOLD)

Neoplasms

Study overall: Recruiting · source record updated 22 May 2026.

4 England locations · 4 explicitly recorded as recruiting.

NCT06561386 · Interventional

A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

Non-small Cell Lung Cancer

Study overall: Recruiting · source record updated 17 August 2026.

9 England locations · 4 explicitly recorded as recruiting.

NCT06584357 · Observational

Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia

Mild Cognitive Impairment · Alzheimer's Disease · Alzheimer's Disease, Early Onset · Memory Loss · Memory Disorders · Memory Impairment

Study overall: Recruiting · source record updated 15 April 2026.

2 England locations · 2 explicitly recorded as recruiting.

NCT06611306 · Interventional

BEAT-Breast: Trial of DE-iPTV in Patients With Primary Breast Cancer With Brain Metastases Who Are Not Suitable for Stereotactic Radiotherapy.

Brain Metastases, Adult · Breast Cancer

Study overall: Not yet recruiting · source record updated 15 October 2024.

1 England locations · 0 explicitly recorded as recruiting.

NCT06613698 · Interventional

A Study to Investigate the Safety and Efficacy of GSK4532990 Compared With Placebo in Adult Participants Aged 18 to 70 Years With Alcohol-related Liver Disease

Liver Diseases, Alcoholic

Study overall: Recruiting · source record updated 3 August 2026.

8 England locations · 8 explicitly recorded as recruiting.

NCT06639828 · Interventional

Phase 4 Paediatric Study to Evaluate Sonazoid Safety and Efficacy for Contrast-Enhanced Ultrasound Liver Imaging

Focal Liver Lesions

Study overall: Recruiting · source record updated 4 March 2026.

3 England locations · 3 explicitly recorded as recruiting.

NCT06641466 · Interventional

A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual Migraine

Menstrual Migraine

Study overall: Recruiting · source record updated 9 July 2026.

7 England locations · 7 explicitly recorded as recruiting.

NCT06644781 · Interventional

A Study of Ifinatamab Deruxtecan in Subjects With Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC) (IDeate-Esophageal01)

Esophageal Squamous Cell Carcinoma

Study overall: Recruiting · source record updated 4 August 2026.

6 England locations · 6 explicitly recorded as recruiting.

NCT06697301 · Interventional

Safety and Efficacy of EIK1001 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.

Advanced Melanoma

Study overall: Recruiting · source record updated 8 May 2026.

3 England locations · 3 explicitly recorded as recruiting.

NCT06717295 · Observational

The CCANED-CIPHER Study: Early Cancer Detection and Treatment Response Monitoring Using AI-Based Platelet and Immune Cell Transcriptomic Profiling

Brest Cancer · Lung Cancer (NSCLC) · Pancreatic Cancer, Adult · Prostate Cancers · Ovarian Cancer · Colorectal Cancer · Glioblastoma (GBM) · Liver Carcinoma

Study overall: Recruiting · source record updated 2 January 2026.

2 England locations · 1 explicitly recorded as recruiting.

NCT06750016 · Observational

Non-invasive Detection of Coronary Artery Stenosis

Coronary Arterial Disease (CAD)

Study overall: Not yet recruiting · source record updated 27 December 2024.

1 England locations · 0 explicitly recorded as recruiting.

NCT06764875 · Interventional

A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer

HER2-positive Gastric Cancer · Gastroesophageal Junction Adenocarcinoma

Study overall: Recruiting · source record updated 16 June 2026.

6 England locations · 6 explicitly recorded as recruiting.

NCT06789406 · Interventional

PMCF Study of the Axonics SNM System Model 5101 (R20) for the Indication of OAB

Urinary Urge Incontinence (UUI) · Urinary Frequency (UF) · Overactive Bladder (OAB)

Study overall: Recruiting · source record updated 12 August 2026.

4 England locations · 4 explicitly recorded as recruiting.

NCT06793215 · Interventional

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer · KRAS G12C Lung Cancer

Study overall: Recruiting · source record updated 8 September 2026.

10 England locations · 10 explicitly recorded as recruiting.

NCT06793397 · Interventional

A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

Major Depressive Disorder (MDD) · Depression in Adults · Depression - Major Depressive Disorder · Depression Disorders · Depression Disorder · Depression

Study overall: Recruiting · source record updated 26 August 2026.

10 England locations · 9 explicitly recorded as recruiting.

NCT06795789 · Interventional

Multivitamin Intervention and Cognitive Function

Healthy Adult · Cognitive Measures

Study overall: Not yet recruiting · source record updated 28 January 2025.

1 England locations · 0 explicitly recorded as recruiting.

NCT06803771 · Interventional

Surveillance of Pancreatic Health After Diabetes Diagnosis

Diabetes Mellitus · Pancreatic Cancer, Adult

Study overall: Recruiting · source record updated 23 March 2026.

31 England locations · 31 explicitly recorded as recruiting.

More ways to explore research

This is a selected international registry feed, not every study taking place in England. NIHR also lists participation opportunities, including studies that may not appear in this selection.

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Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).

Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.

How we selected and connected these records

Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.