NCT06793215 · Krascendo 2
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
Registered research study with 10 identifiable England locations. See source dates, location-specific recruitment and the original study record.
Study facts
- Conditions recorded
- Non-Small Cell Lung Cancer; KRAS G12C Lung Cancer
- Lead sponsor
- Hoffmann-La Roche
- Study type
- Interventional
- Overall status
- Recruiting · this can differ by location
- Age range in the record
- 18 Years to Not specified
- Sex eligibility field
- All
- Healthy volunteers accepted
- No, according to the record
- Phase
- Phase3
- Study record last updated
- 8 September 2026
- Study team last verified status
- 2026-09
These fields are a starting point. Eligibility can include diagnosis, treatment history and other criteria shown only in the complete source record. A registry entry does not establish treatment effectiveness.
England study locations
A location is reproduced as named in the study record. A source map point can represent a town; it is not used here as a hospital entrance or to identify a care provider.
| Location in the source | Local recruitment status | Geographic connection |
|---|---|---|
| Blackpool Teaching Hospitals NHS Foundation Trust , Victoria Hospital Blackpool · FY3 8NR | Recruiting | Care in Blackpool England postcode |
| Bristol Haematology & Oncology Centre Bristol · BS2 8ED | Recruiting | Care in Bristol England postcode |
| East Kent Hospitals University NHS Foundation Trust Canterbury · CT1 3NG | Recruiting | Care in Canterbury England postcode |
| Hull University Teaching Hospitals NHS Trust Hull · HU3 2JZ | Recruiting | Care in Kingston upon Hull England postcode |
| Barts and the London NHS Trust London · E1 2ES | Recruiting | Care in Tower Hamlets England postcode |
| Royal Marsden Hospital - Fulham London · SW3 6JJ | Recruiting | Care in Kensington and Chelsea England postcode |
| Sarah Cannon Research Institute London · W1G 6AD | Recruiting | Care in Westminster England postcode |
| Maidstone and Tunbridge Wells NHS Trust Maidstone · ME16 9QQ | Recruiting | Care in Maidstone England postcode |
| Oxford University Hospitals NHS Trust - Churchill Hospital Oxford · OX3 7LE | Recruiting | Care in Oxford England postcode |
| Royal Marsden NHS Foundation Trust Sutton · SM2 5PT | Recruiting | Care in Sutton England postcode |
Questions for the research team
- Is this exact location currently enrolling participants, and do my circumstances meet the full criteria?
- What visits, tests, possible risks and follow-up would participation involve?
- Are travel costs or accessibility arrangements available?
- How would participation affect my usual care, and what happens if I withdraw?
Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).
Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.
How we selected and connected these records
Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.