RESEARCH IN ENGLAND

Explore clinical trials with England locations

Search 2,970 registered studies with identifiable England locations in our dated ClinicalTrials.gov snapshot. Explore the study and local recruitment details before contacting the research team.

Condition, study or locationRecorded care areaStatus at an England locationClear filters

194 matching studies · ordered by study identifier.

The area filter uses exact source postcodes. Locations without a matched postcode remain in the England-wide results.

NCT06472245 · Interventional

Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor

Patients With Non-Small Cell Lung Cancer

Study overall: Recruiting · source record updated 23 July 2026.

4 England locations · 4 explicitly recorded as recruiting.

NCT06492616 · Interventional

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

Breast Cancer

Study overall: Recruiting · source record updated 17 August 2026.

14 England locations · 14 explicitly recorded as recruiting.

NCT06522737 · Interventional

A Study of Duvelisib Versus Gemcitabine or Bendamustine in Participants With Relapsed/Refractory Nodal T Cell Lymphoma With T Follicular Helper (TFH) Phenotype

Lymphoma

Study overall: Recruiting · source record updated 6 April 2026.

6 England locations · 6 explicitly recorded as recruiting.

NCT06525220 · Interventional

A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR - HN1)

Head and Neck Squamous Cell Carcinoma

Study overall: Recruiting · source record updated 2 June 2026.

10 England locations · 10 explicitly recorded as recruiting.

NCT06531499 · Interventional

A Study of Radiation Dosimetry, Safety, and Tolerability of Extended Lutetium (177Lu) Vipivotide Tetraxetan Treatment in Chemo-naïve Adults With Metastatic Castration-resistant Prostate Cancer: RADIOpharmaceutical DOSimetry Evaluation (RADIODOSE) Study

Metastatic Castration-Resistant Prostate Cancer

Study overall: Recruiting · source record updated 31 December 2025.

2 England locations · 2 explicitly recorded as recruiting.

NCT06556563 · Interventional

EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma

Glioblastoma

Study overall: Recruiting · source record updated 19 August 2026.

9 England locations · 0 explicitly recorded as recruiting.

NCT06567782 · Interventional

A Study of Neoadjuvant Dostarlimab Plus Capecitabine Plus Oxaliplatin (CAPEOX) Vs CAPEOX With Previously Untreated T4N0 or Stage III Mismatch Repair Proficient (MMRp)/Microsatellite Stable (MSS) Colon Cancer

Neoplasms, Colon

Study overall: Recruiting · source record updated 22 May 2026.

3 England locations · 3 explicitly recorded as recruiting.

NCT06585774 · Interventional

A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

Chronic Graft-versus-host-disease

Study overall: Recruiting · source record updated 6 August 2026.

6 England locations · 6 explicitly recorded as recruiting.

NCT06600789 · Interventional

A Modular Phase 1/2 Study With CT7439 in Participants With Solid Malignancies

Solid Malignancies

Study overall: Recruiting · source record updated 3 September 2026.

3 England locations · 3 explicitly recorded as recruiting.

NCT06619587 · Interventional

A Study to Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors

Solid Tumor

Study overall: Recruiting · source record updated 25 August 2026.

3 England locations · 3 explicitly recorded as recruiting.

NCT06630260 · Interventional

5G-RUBY: Avutometinib and Defactinib in Malignant Brain Tumours

Glioblastoma Multiforme (GBM) · Glioblastoma Multiform (Grade IV Astrocytoma) · Diffuse Hemispheric Glioma, H3 G34-Mutant · Malignant Primary Gliomas

Study overall: Recruiting · source record updated 21 January 2026.

3 England locations · 3 explicitly recorded as recruiting.

NCT06630754 · Observational

Body Composition in Older Adults

Sarcopenia in Elderly · Cachexia; Cancer; Sarcopenia · Body Composition Changes · Older Adults · Nutrition

Study overall: Not yet recruiting · source record updated 8 October 2024.

1 England locations · 0 explicitly recorded as recruiting.

NCT06636526 · Observational

The i4i PRODICT® Study: Evaluation of the i4i PRODICT® Test in Different Ethnic Groups (The i4i PRODICT® Study).

Prostate Cancer

Study overall: Recruiting · source record updated 4 February 2026.

3 England locations · 3 explicitly recorded as recruiting.

NCT06641908 · Interventional

Anti-GD2 ADC M3554 in Advanced Solid Tumors

Advanced Solid Tumor

Study overall: Recruiting · source record updated 8 September 2026.

1 England locations · 1 explicitly recorded as recruiting.

NCT06659341 · Interventional

A Phase I Study of BAY3498264 Given Together With Sotorasib in Participants Who Have Advanced Solid Cancers With Specific Genetic Changes Called KRASG12C Mutation

Advanced Solid Tumors Harboring KRAS G12C Mutation

Study overall: Recruiting · source record updated 26 August 2026.

2 England locations · 2 explicitly recorded as recruiting.

NCT06662786 · Interventional

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Colorectal Neoplasms

Study overall: Recruiting · source record updated 28 August 2026.

8 England locations · 8 explicitly recorded as recruiting.

NCT06667076 · Interventional

A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Carcinoma, Non-Small-Cell Lung

Study overall: Recruiting · source record updated 28 August 2026.

6 England locations · 6 explicitly recorded as recruiting.

NCT06712316 · Interventional

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

Non-small Cell Lung Cancer

Study overall: Recruiting · source record updated 4 September 2026.

15 England locations · 15 explicitly recorded as recruiting.

NCT06712355 · Interventional

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

Extensive-stage Small-cell Lung Cancer

Study overall: Recruiting · source record updated 1 September 2026.

16 England locations · 16 explicitly recorded as recruiting.

NCT06764316 · Interventional

A First-in-human Study to Learn About the Safety of BAY 3547926 and How Well it Works in Participants With Advanced Liver Cancer

Hepatocellular Carcinoma

Study overall: Recruiting · source record updated 18 August 2026.

3 England locations · 3 explicitly recorded as recruiting.

More ways to explore research

This is a selected international registry feed, not every study taking place in England. NIHR also lists participation opportunities, including studies that may not appear in this selection.

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Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).

Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.

How we selected and connected these records

Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.