RESEARCH IN ENGLAND

Explore clinical trials with England locations

Search 2,970 registered studies with identifiable England locations in our dated ClinicalTrials.gov snapshot. Explore the study and local recruitment details before contacting the research team.

Condition, study or locationRecorded care areaStatus at an England locationClear filters

230 matching studies · ordered by study identifier.

The area filter uses exact source postcodes. Locations without a matched postcode remain in the England-wide results.

NCT06408441 · Observational

The Epithelioid Hemangioendothelioma Registry of the European Reference Network on Rare Adult Solid Cancers (EURACAN)

Epithelioid Hemangioendothelioma · Sarcoma,Soft Tissue

Study overall: Recruiting · source record updated 3 April 2026.

1 England locations · 1 explicitly recorded as recruiting.

NCT06461897 · Interventional

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

Study overall: Recruiting · source record updated 6 August 2026.

7 England locations · 6 explicitly recorded as recruiting.

NCT06467357 · Interventional

Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer

Biliary Tract Cancer

Study overall: Recruiting · source record updated 19 August 2026.

4 England locations · 4 explicitly recorded as recruiting.

NCT06492616 · Interventional

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

Breast Cancer

Study overall: Recruiting · source record updated 17 August 2026.

14 England locations · 14 explicitly recorded as recruiting.

NCT06511648 · Interventional

Erdafitinib Monotherapy or in Combination With Cetrelimab in Muscle-invasive Bladder Cancer Patients With Fibroblast Growth Factor Receptor (FGFR ) Gene Alterations

Muscle-invasive Bladder Cancer

Study overall: Recruiting · source record updated 19 December 2025.

5 England locations · 4 explicitly recorded as recruiting.

NCT06514612 · Interventional

LIDRISE Study: A Phase 3 Study on the Efficacy and Safety of STN1013800 (Oxymetazoline HCl 0.1% Eye Drops, Single Dose) in the Treatment of Acquired Blepharoptosis.

Acquired Blepharophimosis

Study overall: Recruiting · source record updated 4 May 2026.

6 England locations · 6 explicitly recorded as recruiting.

NCT06525220 · Interventional

A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR - HN1)

Head and Neck Squamous Cell Carcinoma

Study overall: Recruiting · source record updated 2 June 2026.

10 England locations · 10 explicitly recorded as recruiting.

NCT06528314 · Interventional

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

NASH - Nonalcoholic Steatohepatitis · MASH - Metabolic Dysfunction-Associated Steatohepatitis

Study overall: Recruiting · source record updated 8 September 2026.

7 England locations · 7 explicitly recorded as recruiting.

NCT06545227 · Observational

Early Versus Late Monitoring Among Pregnant Women With a History of Gestational Diabetes

Pregnancy Complications · Gestational Diabetes

Study overall: Recruiting · source record updated 9 August 2024.

1 England locations · 1 explicitly recorded as recruiting.

NCT06549946 · Interventional

Ixovex-1 Single Agent and Combination Therapy

Solid Tumor · Head and Neck Cancer

Study overall: Recruiting · source record updated 30 January 2025.

1 England locations · 1 explicitly recorded as recruiting.

NCT06559150 · Interventional

A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis

Non-cystic Fibrosis Bronchiectasis

Study overall: Recruiting · source record updated 6 August 2026.

5 England locations · 5 explicitly recorded as recruiting.

NCT06560905 · Interventional

Preoperative Planning With PSMA-PET in Melanoma Surgery Trial

Malignant Melanoma

Study overall: Recruiting · source record updated 1 July 2025.

1 England locations · 1 explicitly recorded as recruiting.

NCT06561386 · Interventional

A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

Non-small Cell Lung Cancer

Study overall: Recruiting · source record updated 17 August 2026.

9 England locations · 4 explicitly recorded as recruiting.

NCT06572384 · Interventional

A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease

Lung Diseases, Interstitial

Study overall: Recruiting · source record updated 8 September 2026.

3 England locations · 3 explicitly recorded as recruiting.

NCT06576271 · Interventional

A Study of GSK4527363 in Healthy Participants, Systemic Lupus Erythematosus (SLE) Participants, Healthy Chinese, and Japanese Participants and CTD-ILD Participants

Systemic Lupus Erythematosus

Study overall: Recruiting · source record updated 22 June 2026.

4 England locations · 4 explicitly recorded as recruiting.

NCT06579443 · Observational

Robotic Inflammatory Bowel Disease Development, Learning and Efficacy Study

Inflammatory Bowel Diseases · Crohn Disease · Ulcerative Colitis

Study overall: Recruiting · source record updated 10 December 2025.

6 England locations · 6 explicitly recorded as recruiting.

NCT06581406 · Interventional

A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

Metastatic Uveal Melanoma

Study overall: Recruiting · source record updated 2 April 2026.

2 England locations · 2 explicitly recorded as recruiting.

NCT06590467 · Observational

Abbott Structural Heart Device Registry

Heart Diseases · ASD - Atrial Septal Defect · VSD - Muscular Ventricular Septal Defect · PFO - Patent Foramen Ovale · PIVSD - Post Infarct Muscular Ventricular Septal Defect · Valvular Heart Disease

Study overall: Recruiting · source record updated 1 September 2026.

2 England locations · 2 explicitly recorded as recruiting.

NCT06623422 · Interventional

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

Carcinoma, Non-Small-Cell Lung

Study overall: Recruiting · source record updated 27 August 2026.

12 England locations · 12 explicitly recorded as recruiting.

NCT06627647 · Interventional

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC

Non-squamous Non-small Cell Lung Cancer

Study overall: Recruiting · source record updated 14 August 2026.

8 England locations · 7 explicitly recorded as recruiting.

More ways to explore research

This is a selected international registry feed, not every study taking place in England. NIHR also lists participation opportunities, including studies that may not appear in this selection.

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Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).

Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.

How we selected and connected these records

Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.