NCT04723316 · Observational
Tumour Characterisation to Guide Experimental Targeted Therapy - National
Cancer
Study overall: Recruiting · source record updated 7 February 2024.
16 England locations · 15 explicitly recorded as recruiting.
RESEARCH IN ENGLAND
Explore clinical trials with England locations
Search 2,970 registered studies with identifiable England locations in our dated ClinicalTrials.gov snapshot. Explore the study and local recruitment details before contacting the research team.
159 matching studies · ordered by study identifier.
The area filter uses exact source postcodes. Locations without a matched postcode remain in the England-wide results.
NCT04817618 · Interventional
Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.
C3G
Study overall: Recruiting · source record updated 13 July 2026.
3 England locations · 0 explicitly recorded as recruiting.
NCT04877522 · Interventional
Asciminib Roll-over Study
Chronic Myelogenous Leukemia · Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Study overall: Recruiting · source record updated 6 July 2026.
2 England locations · 2 explicitly recorded as recruiting.
NCT04879329 · Interventional
A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2
Urothelial Carcinoma
Study overall: Recruiting · source record updated 22 July 2026.
7 England locations · 5 explicitly recorded as recruiting.
NCT04888741 · Interventional
Methods of T Cell Depletion Trial (MoTD)
Acute Myeloid Leukemia · Acute Lymphoblastic Leukemia · Chronic Myelomonocytic Leukemia · Myelodysplastic Syndromes · Non Hodgkin Lymphoma · Hodgkin Lymphoma · Multiple Myeloma · Chronic Myelogenous Leukemia · Myelofibrosis
Study overall: Recruiting · source record updated 5 May 2026.
15 England locations · 15 explicitly recorded as recruiting.
NCT05070845 · Interventional
Safety and Efficacy Study of PF-06835375 in Primary Immune Thrombocytopenia
Primary Immune Thrombocytopenia
Study overall: Recruiting · source record updated 12 May 2026.
4 England locations · 4 explicitly recorded as recruiting.
NCT05102019 · Interventional
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II
Refractory Angina
Study overall: Recruiting · source record updated 26 August 2026.
20 England locations · 20 explicitly recorded as recruiting.
NCT05176483 · Interventional
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
Renal Cell Carcinoma (RCC) · Metastatic Castration-Resistant Prostate Cancer (mCRPC) · Urothelial Carcinoma (UC) · Solid Tumor · Hepatocellular Carcinoma (HCC) · Non-small Cell Lung Cancer (NSCLC) · Colorectal Cancer (CRC) · Head and Neck Squamous Cell Carcinoma (HNSCC) · Clear Cell Renal Cell Carcinoma (ccRCC) · Non-Clear Cell Renal Cell Carcinoma (nccRCC) · Drug-Drug Interaction (DDI)
Study overall: Recruiting · source record updated 5 August 2026.
3 England locations · 3 explicitly recorded as recruiting.
NCT05178693 · Interventional
Lutathera and ASTX727 in Neuroendocrine Tumours
Neuroendocrine Tumors
Study overall: Recruiting · source record updated 24 November 2025.
1 England locations · 1 explicitly recorded as recruiting.
NCT05253651 · Interventional
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
Colorectal Neoplasms
Study overall: Recruiting · source record updated 22 July 2026.
10 England locations · 10 explicitly recorded as recruiting.
NCT05254171 · Interventional
Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer
Pancreatic Cancer Metastatic · Pancreatic Ductal Adenocarcinoma · Pancreatic Cancer Stage IV
Study overall: Recruiting · source record updated 6 November 2024.
2 England locations · 2 explicitly recorded as recruiting.
NCT05304377 · Interventional
A Phase 1a/1b Study of ELVN-001 for the Treatment Chronic Myeloid Leukemia
Chronic Myeloid Leukemia · Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive · Cml
Study overall: Recruiting · source record updated 1 April 2026.
2 England locations · 2 explicitly recorded as recruiting.
NCT05318794 · Interventional
Neoadjuvant Systemic and Peritoneal Chemotherapy for Advanced Gastric Cancer
Gastric Cancer · Peritoneal Metastases · Chemotherapy Effect
Study overall: Not yet recruiting · source record updated 13 September 2023.
1 England locations · 0 explicitly recorded as recruiting.
NCT05404061 · Interventional
The Poor Responders Study
Bariatric Surgery Candidate · Obesity, Morbid · Diabetes Mellitus, Type 2
Study overall: Recruiting · source record updated 9 May 2025.
1 England locations · 1 explicitly recorded as recruiting.
NCT05412758 · Interventional
Augmented Response of Volatile Biomarkers in Assessment of Oesophagogastric Cancer (AROMA 1 / BIORESOURCE)
Volatile Organic Compounds · Microbiome · Microbioata · Breath Analysis · Oesophageal Cancer · Gastric Cancer · Volatalomics · Metabonomics/Lipidomics · Microbiome Analysis · Transcriptomics
Study overall: Recruiting · source record updated 31 January 2025.
1 England locations · 1 explicitly recorded as recruiting.
NCT05431088 · Interventional
A Phase 2/3 Study of Osivelotor in Adult and Adolescent Participants With SCD
Sickle Cell Disease
Study overall: Recruiting · source record updated 18 August 2026.
7 England locations · 7 explicitly recorded as recruiting.
NCT05485961 · Interventional
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
End Stage Kidney Disease
Study overall: Recruiting · source record updated 11 August 2026.
14 England locations · 12 explicitly recorded as recruiting.
NCT05487612 · Interventional
MiECC Versus Conventional Cardiopulmonary Bypass in Cardiac Surgery (MiECS)
Coronary Artery Disease · Aortic Valve Stenosis · Extracorporeal Circulation; Complications
Study overall: Recruiting · source record updated 30 March 2026.
3 England locations · 0 explicitly recorded as recruiting.
NCT05489705 · Observational
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
Obstructive Hypertrophic Cardiomyopathy
Study overall: Recruiting · source record updated 19 August 2026.
6 England locations · 4 explicitly recorded as recruiting.
NCT05519085 · Interventional
A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
Relapsed or Refractory Multiple Myeloma
Study overall: Recruiting · source record updated 9 September 2026.
8 England locations · 8 explicitly recorded as recruiting.
More ways to explore research
This is a selected international registry feed, not every study taking place in England. NIHR also lists participation opportunities, including studies that may not appear in this selection.
Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).
Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.
How we selected and connected these records
Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.