NCT05253651 · MOUNTAINEER-03
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
Registered research study with 10 identifiable England locations. See source dates, location-specific recruitment and the original study record.
Study facts
- Conditions recorded
- Colorectal Neoplasms
- Lead sponsor
- Seagen, a wholly owned subsidiary of Pfizer
- Study type
- Interventional
- Overall status
- Recruiting · this can differ by location
- Age range in the record
- 18 Years to Not specified
- Sex eligibility field
- All
- Healthy volunteers accepted
- No, according to the record
- Phase
- Phase3
- Study record last updated
- 22 July 2026
- Study team last verified status
- 2026-07
These fields are a starting point. Eligibility can include diagnosis, treatment history and other criteria shown only in the complete source record. A registry entry does not establish treatment effectiveness.
England study locations
A location is reproduced as named in the study record. A source map point can represent a town; it is not used here as a hospital entrance or to identify a care provider.
| Location in the source | Local recruitment status | Geographic connection |
|---|---|---|
| The Newcastle upon Tyne Hospitals NHS Foundation Trust Newcastle upon Tyne · NE7 7DN | Recruiting | Care in Newcastle upon Tyne England postcode |
| The Royal Marsden Hospital Sutton · SM2 5PT | Recruiting | Care in Sutton England postcode |
| University Hospitals Bristol and Weston NHS Foundation Trust Bristol · BS2 8ED | Recruiting | Care in Bristol England postcode |
| Cambridge University Hospitals NHS Foundation Trust, Oncology Centre Cambridge · CB2 0QQ | Recruiting | Care in Cambridge England postcode |
| Leeds Teaching Hospitals NHS Trust, st James's Institute of Oncology Leeds · LS97TF | Recruiting | Care in Leeds England postcode |
| Guy's and Saint Thomas' NHS Foundation Trust London · SE1 9RT | Recruiting | Care in Southwark England postcode |
| The Royal Marsden Hospital - Chelsea Site London · SW3 6JJ | Recruiting | Care in Kensington and Chelsea England postcode |
| The Royal Marsden NHS Foundation Trust London · SW3 6JJ | Recruiting | Care in Kensington and Chelsea England postcode |
| Imperial College Healthcare NHS Trust London · W12 0NN | Recruiting | Care in Hammersmith and Fulham England postcode |
| The Christie NHS Foundation Trust Manchester · M20 4BX | Recruiting | Care in Manchester England postcode |
Questions for the research team
- Is this exact location currently enrolling participants, and do my circumstances meet the full criteria?
- What visits, tests, possible risks and follow-up would participation involve?
- Are travel costs or accessibility arrangements available?
- How would participation affect my usual care, and what happens if I withdraw?
Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).
Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.
How we selected and connected these records
Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.