NCT04723316 · Observational
Tumour Characterisation to Guide Experimental Targeted Therapy - National
Cancer
Study overall: Recruiting · source record updated 7 February 2024.
16 England locations · 15 explicitly recorded as recruiting.
RESEARCH IN ENGLAND
Explore clinical trials with England locations
Search 2,970 registered studies with identifiable England locations in our dated ClinicalTrials.gov snapshot. Explore the study and local recruitment details before contacting the research team.
479 matching studies · ordered by study identifier.
The area filter uses exact source postcodes. Locations without a matched postcode remain in the England-wide results.
NCT04772079 · Interventional
A Study to Evaluate the Drug Levels, Efficacy and Safety of Deucravacitinib in Children and Adolescent Participants With Moderate to Severe Plaque Psoriasis
Plaque Psoriasis
Study overall: Recruiting · source record updated 18 August 2026.
3 England locations · 1 explicitly recorded as recruiting.
NCT04775485 · Interventional
A Study to Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors
Low-grade Glioma · Advanced Solid Tumor
Study overall: Recruiting · source record updated 10 April 2025.
2 England locations · 2 explicitly recorded as recruiting.
NCT04779320 · Interventional
A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)
Crohn's Disease (CD)
Study overall: Recruiting · source record updated 5 May 2026.
5 England locations · 0 explicitly recorded as recruiting.
NCT04782258 · Interventional
A Study to See if Tolvaptan is Safe in Infants and Children Who at Enrollment Are 28 Days to Less Than 18 Years Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD)
Autosomal Recessive Polycystic Kidney (ARPKD)
Study overall: Recruiting · source record updated 7 August 2026.
1 England locations · 1 explicitly recorded as recruiting.
NCT04798261 · Observational
Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System
Pulmonary Embolism
Study overall: Recruiting · source record updated 6 July 2026.
2 England locations · 2 explicitly recorded as recruiting.
NCT04808505 · Interventional
A Study to Evaluate the Safety, Efficacy, PK, PD and Immunogenicity of Cipaglucosidase Alfa/Miglustat in IOPD Subjects Aged 0 to <18
Glycogen Storage Disease Type II Infantile Onset
Study overall: Recruiting · source record updated 22 January 2026.
1 England locations · 1 explicitly recorded as recruiting.
NCT04811560 · Interventional
A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)
Acute Leukemia
Study overall: Recruiting · source record updated 28 August 2026.
7 England locations · 7 explicitly recorded as recruiting.
NCT04817462 · Interventional
Liver Biopsy In Haemophilia Gene Therapy
Hemophilia B, Severe · Hemophilia A, Severe
Study overall: Recruiting · source record updated 20 December 2024.
1 England locations · 1 explicitly recorded as recruiting.
NCT04817618 · Interventional
Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.
C3G
Study overall: Recruiting · source record updated 13 July 2026.
3 England locations · 0 explicitly recorded as recruiting.
NCT04833894 · Interventional
Evaluating the Pharmacokinetics, Pharmacodynamics, and Safety of Efgartigimod Administered Intravenously in Children With Generalized Myasthenia Gravis
Generalized Myasthenia Gravis
Study overall: Recruiting · source record updated 18 February 2026.
3 England locations · 3 explicitly recorded as recruiting.
NCT04888741 · Interventional
Methods of T Cell Depletion Trial (MoTD)
Acute Myeloid Leukemia · Acute Lymphoblastic Leukemia · Chronic Myelomonocytic Leukemia · Myelodysplastic Syndromes · Non Hodgkin Lymphoma · Hodgkin Lymphoma · Multiple Myeloma · Chronic Myelogenous Leukemia · Myelofibrosis
Study overall: Recruiting · source record updated 5 May 2026.
15 England locations · 15 explicitly recorded as recruiting.
NCT04892654 · Interventional
Efficacy of Doravirine + Dolutegravir Dual Therapy in the Context of Antiretroviral Therapy Switch
HIV-1-infection
Study overall: Recruiting · source record updated 25 October 2023.
3 England locations · 3 explicitly recorded as recruiting.
NCT04910568 · Interventional
A Study Evaluating the Safety, Pharmacokinetics, and Activity of Cevostamab in Participants With Relapsed or Refractory Multiple Myeloma
Multiple Myeloma
Study overall: Recruiting · source record updated 20 August 2026.
2 England locations · 0 explicitly recorded as recruiting.
NCT04910685 · Interventional
(HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With Indolent Systemic Mastocytosis
Indolent Systemic Mastocytosis · Smoldering Systemic Mastocytosis
Study overall: Recruiting · source record updated 4 August 2026.
4 England locations · 4 explicitly recorded as recruiting.
NCT04924075 · Interventional
Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)
Pheochromocytoma/Paraganglioma · Pancreatic Neuroendocrine Tumor · Von Hippel-Lindau Disease · Advanced Gastrointestinal Stromal Tumor · HIF-2α Mutated Cancers
Study overall: Recruiting · source record updated 3 September 2026.
3 England locations · 2 explicitly recorded as recruiting.
NCT04928846 · Interventional
A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
Non Small Cell Lung Cancer
Study overall: Recruiting · source record updated 9 September 2026.
6 England locations · 6 explicitly recorded as recruiting.
NCT04929223 · Interventional
A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)
Metastatic Colorectal Cancer
Study overall: Recruiting · source record updated 17 August 2026.
7 England locations · 6 explicitly recorded as recruiting.
NCT04939935 · Interventional
Implementation of Metformin theraPy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD)
Autosomal Dominant Polycystic Kidney Disease
Study overall: Recruiting · source record updated 31 March 2026.
25 England locations · 15 explicitly recorded as recruiting.
NCT04965298 · Interventional
Treating People With Idiopathic Pulmonary Fibrosis With the Addition of Lansoprazole
Idiopathic Pulmonary Fibrosis
Study overall: Recruiting · source record updated 22 December 2025.
50 England locations · 36 explicitly recorded as recruiting.
More ways to explore research
This is a selected international registry feed, not every study taking place in England. NIHR also lists participation opportunities, including studies that may not appear in this selection.
Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).
Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.
How we selected and connected these records
Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.