RESEARCH IN ENGLAND

Explore clinical trials with England locations

Search 2,970 registered studies with identifiable England locations in our dated ClinicalTrials.gov snapshot. Explore the study and local recruitment details before contacting the research team.

Condition, study or locationRecorded care areaStatus at an England locationClear filters

479 matching studies · ordered by study identifier.

The area filter uses exact source postcodes. Locations without a matched postcode remain in the England-wide results.

NCT06680830 · Interventional

A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

Parkinson Disease · Parkinson · Idiopathic Parkinson Disease · Early Parkinson Disease (Early PD) · Parkinson Disease, Idiopathic

Study overall: Recruiting · source record updated 28 August 2026.

5 England locations · 3 explicitly recorded as recruiting.

NCT06682988 · Interventional

A Study to Assess Adverse Events and Change in Disease Activity in Participants With Platinum-Resistant Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha Expression Treated With Intravenously (IV) Infused Mirvetuximab Soravtansine

Advanced High-Grade Epithelial Ovarian Cancer · Primary Peritoneal Cancer · Fallopian Tube Cancers

Study overall: Recruiting · source record updated 26 May 2026.

3 England locations · 3 explicitly recorded as recruiting.

NCT06686394 · Interventional

Study of Patritumab Deruxtecan With Other Anticancer Agents in Participants With HER2 Positive Breast Cancer That Has Spread and Cannot Be Surgically Removed (MK-1022-009)

Breast Neoplasms · Breast Cancer

Study overall: Recruiting · source record updated 22 May 2026.

2 England locations · 2 explicitly recorded as recruiting.

NCT06711692 · Observational

The U.K. NorthStar Clinical Network

Duchenne Muscular Dystrophy

Study overall: Not yet recruiting · source record updated 2 December 2024.

19 England locations · 0 explicitly recorded as recruiting.

NCT06712823 · Interventional

An Extension Study to Evaluate Safety and Efficacy of Atumelnant in Participants With Congenital Adrenal Hyperplasia

Congenital Adrenal Hyperplasia · Classic Congenital Adrenal Hyperplasia

Study overall: Recruiting · source record updated 29 June 2026.

2 England locations · 2 explicitly recorded as recruiting.

NCT06716606 · Interventional

A Study to Investigate the Long-term Safety and Efficacy of Belimumab in Adults With Interstitial Lung Disease (ILD) Associated With Systemic Sclerosis (SSc) and Other Connective Tissue Diseases (CTD) (BLISSconneCTD-OLE)

Connective Tissue Diseases

Study overall: Recruiting · source record updated 9 September 2026.

2 England locations · 2 explicitly recorded as recruiting.

NCT06717919 · Interventional

HOPE Against Cancer Recurrence in HCC

Liver Transplantation · HCC · Oncological Outcomes

Study overall: Recruiting · source record updated 16 December 2025.

5 England locations · 0 explicitly recorded as recruiting.

NCT06722235 · Interventional

A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

Immune Thrombocytopenic Purpura (ITP)

Study overall: Recruiting · source record updated 7 August 2026.

9 England locations · 9 explicitly recorded as recruiting.

NCT06726213 · Interventional

Walk and Talk: Connecting People With Psoriasis

Psoriasis · Social Isolation

Study overall: Recruiting · source record updated 10 December 2024.

1 England locations · 1 explicitly recorded as recruiting.

NCT06727604 · Interventional

A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

Graves' Disease

Study overall: Recruiting · source record updated 25 August 2026.

12 England locations · 12 explicitly recorded as recruiting.

NCT06742996 · Interventional

A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)

Mantle Cell Lymphoma · B Cell Lymphoma

Study overall: Recruiting · source record updated 19 August 2026.

6 England locations · 6 explicitly recorded as recruiting.

NCT06744920 · Interventional

A Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib Versus Placebo in Adult Patients With Generalized Myasthenia Gravis

Generalized Myasthenia Gravis

Study overall: Recruiting · source record updated 29 July 2026.

2 England locations · 1 explicitly recorded as recruiting.

NCT06745908 · Interventional

Clinical Trial of N-803 Plus Tislelizumab or Prior Failed Immune Checkpoint Inhibitor and Docetaxel Versus Docetaxel Monotherapy in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Acquired Resistance to Immune Checkpoint In

NSCLC Stage IV

Study overall: Recruiting · source record updated 27 July 2026.

5 England locations · 5 explicitly recorded as recruiting.

NCT06750094 · Interventional

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

Colorectal Neoplasms

Study overall: Recruiting · source record updated 28 August 2026.

7 England locations · 7 explicitly recorded as recruiting.

NCT06760546 · Interventional

A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)

Hypothalamic Obesity · Multiple Pituitary Hormone Deficiency Genetic Form · Septo-Optic Dysplasia · Optic Nerve Hypoplasia · Childhood-onset Combined Pituitary Hormone Deficiency · Pituitary Stalk Interruption Syndrome

Study overall: Recruiting · source record updated 12 February 2026.

3 England locations · 3 explicitly recorded as recruiting.

NCT06764316 · Interventional

A First-in-human Study to Learn About the Safety of BAY 3547926 and How Well it Works in Participants With Advanced Liver Cancer

Hepatocellular Carcinoma

Study overall: Recruiting · source record updated 18 August 2026.

3 England locations · 3 explicitly recorded as recruiting.

NCT06765109 · Interventional

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

Non-small Cell Lung Cancer · Anaplastic Lymphoma Kinase-positive

Study overall: Recruiting · source record updated 25 August 2026.

8 England locations · 8 explicitly recorded as recruiting.

NCT06770335 · Interventional

The FLaME Cognitive Rehabilitation Study for Childhood Brain Tumour

Childhood Brain Tumor · Childhood Brain Tumors · Pediatric Brain Neoplasms · Pediatric Brain Tumor

Study overall: Not yet recruiting · source record updated 13 January 2025.

1 England locations · 0 explicitly recorded as recruiting.

NCT06780137 · Interventional

A Study to Evaluate the Safety and Efficacy of Gocatamig (MK-6070) and Ifinatamab Deruxtecan (I-DXd) in Participants With Relapsed/Refractory Extensive-Stage Small Cell Lung Cancer (MK-6070-002)

Small Cell Lung Cancer

Study overall: Recruiting · source record updated 9 September 2026.

3 England locations · 0 explicitly recorded as recruiting.

NCT06788990 · Interventional

FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

Metastatic Head and Neck Squamous Cell Carcinoma · Recurrent Head and Neck Squamous Cell Carcinoma

Study overall: Recruiting · source record updated 17 July 2026.

12 England locations · 12 explicitly recorded as recruiting.

More ways to explore research

This is a selected international registry feed, not every study taking place in England. NIHR also lists participation opportunities, including studies that may not appear in this selection.

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Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).

Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.

How we selected and connected these records

Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.