NCT06985706 · DAME
Anti-vascular Endothelial Growth Factor (Anti-VEGF) Monotherapy vs Anti-VEGF Followed by Subthreshold Micropulse Laser for Treating Severe Diabetic Macular Oedema When the Central Retina Goes <400 Microns
Registered research study with 19 identifiable England locations. See source dates, location-specific recruitment and the original study record.
Study facts
- Conditions recorded
- Severe Diabetic Macular Oedema
- Lead sponsor
- Belfast Health and Social Care Trust
- Study type
- Interventional
- Overall status
- Recruiting · this can differ by location
- Age range in the record
- 18 Years to Not specified
- Sex eligibility field
- All
- Healthy volunteers accepted
- No, according to the record
- Phase
- Phase3
- Study record last updated
- 19 September 2025
- Study team last verified status
- 2025-05
These fields are a starting point. Eligibility can include diagnosis, treatment history and other criteria shown only in the complete source record. A registry entry does not establish treatment effectiveness.
England study locations
A location is reproduced as named in the study record. A source map point can represent a town; it is not used here as a hospital entrance or to identify a care provider.
| Location in the source | Local recruitment status | Geographic connection |
|---|---|---|
| Birmingham and Midland Eye Centre Birmingham | Not yet recruiting | England location Source location point within ONS England boundary |
| Sussex Eye Hospital Brighton | Not yet recruiting | England location Source location point within ONS England boundary |
| Bristol Eye Hospital Bristol | Not yet recruiting | England location Source location point within ONS England boundary |
| Frimley Park Hospital Camberley | Recruiting | England location Source location point within ONS England boundary |
| Gloucestershire Royal Hospital Gloucester | Recruiting | England location Source location point within ONS England boundary |
| Hull Royal Infirmary Hull | Not yet recruiting | England location Source location point within ONS England boundary |
| Hinchingbrooke Hospital Huntingdon | Not yet recruiting | England location Source location point within ONS England boundary |
| Royal Liverpool University Hospital Liverpool | Recruiting | England location Source location point within ONS England boundary |
| Central Middlesex Hospital London | Recruiting | England location Source location point within ONS England boundary |
| Chelsea and Westminster Hospital London | Not yet recruiting | England location Source location point within ONS England boundary |
| Kings College Hospital London | Recruiting | England location Source location point within ONS England boundary |
| Moorfields Eye Hospital London | Recruiting | England location Source location point within ONS England boundary |
| James Cook Hospital Middlesbrough | Recruiting | England location Source location point within ONS England boundary |
| Queen's Medical Centre Nottingham | Not yet recruiting | England location Source location point within ONS England boundary |
| East Surrey Hospital Redhill | Not yet recruiting | England location Source location point within ONS England boundary |
| University Hospital Southampton Southampton | Not yet recruiting | England location Source location point within ONS England boundary |
| Sunderland Eye Hospital Sunderland | Recruiting | England location Source location point within ONS England boundary |
| Torbay Hospital Torquay | Not yet recruiting | England location Source location point within ONS England boundary |
| Hillingdon Hospital Uxbridge | Recruiting | England location Source location point within ONS England boundary |
Questions for the research team
- Is this exact location currently enrolling participants, and do my circumstances meet the full criteria?
- What visits, tests, possible risks and follow-up would participation involve?
- Are travel costs or accessibility arrangements available?
- How would participation affect my usual care, and what happens if I withdraw?
Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).
Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.
How we selected and connected these records
Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.