NCT06952504 · TroFuse-033
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
Registered research study with 9 identifiable England locations. See source dates, location-specific recruitment and the original study record.
Study facts
- Conditions recorded
- Endometrial Cancer
- Lead sponsor
- Merck Sharp & Dohme LLC
- Study type
- Interventional
- Overall status
- Recruiting · this can differ by location
- Age range in the record
- 18 Years to Not specified
- Sex eligibility field
- Female
- Healthy volunteers accepted
- No, according to the record
- Phase
- Phase3
- Study record last updated
- 28 August 2026
- Study team last verified status
- 2026-08
These fields are a starting point. Eligibility can include diagnosis, treatment history and other criteria shown only in the complete source record. A registry entry does not establish treatment effectiveness.
England study locations
A location is reproduced as named in the study record. A source map point can represent a town; it is not used here as a hospital entrance or to identify a care provider.
| Location in the source | Local recruitment status | Geographic connection |
|---|---|---|
| University Hospitals Sussex NHS Foundation Trust ( Site 4011) East Sussex · BN2 1ES | Recruiting | Care in The City of Brighton and Hove England postcode |
| Addenbrookes Hospital ( Site 4002) Cambridge · CB2 0QQ | Recruiting | Care in Cambridge England postcode |
| University College London Hospital ( Site 4001) London · NW1 2PG | Recruiting | Care in Camden England postcode |
| ROYAL MARSDEN HOSPITAL (CHELSEA) ( Site 4006) London · SW3 6JJ | Recruiting | Care in Kensington and Chelsea England postcode |
| Hammersmith Hospital ( Site 4010) London · W12 0HS | Recruiting | Care in Hammersmith and Fulham England postcode |
| Royal Marsden Hospital (Sutton) ( Site 4005) London · SM3 5PT | Recruiting | England location Source location point within ONS England boundary |
| Leicester Royal Infirmary ( Site 4008) Leicester · LE1 5WW | Recruiting | Care in Leicester England postcode |
| Maidstone Hospital ( Site 4007) Maidstone · ME16 9QQ | Recruiting | Care in Maidstone England postcode |
| The Christie NHS Foundation Trust ( Site 4003) Manchester · M20 4BX | Recruiting | Care in Manchester England postcode |
Questions for the research team
- Is this exact location currently enrolling participants, and do my circumstances meet the full criteria?
- What visits, tests, possible risks and follow-up would participation involve?
- Are travel costs or accessibility arrangements available?
- How would participation affect my usual care, and what happens if I withdraw?
Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).
Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.
How we selected and connected these records
Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.