NCT05580562 · ACTION
ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)
Registered research study with 10 identifiable England locations. See source dates, location-specific recruitment and the original study record.
Study facts
- Conditions recorded
- H3 K27M; Glioma
- Lead sponsor
- Jazz Pharmaceuticals
- Study type
- Interventional
- Overall status
- Recruiting · this can differ by location
- Age range in the record
- Not specified to Not specified
- Sex eligibility field
- All
- Healthy volunteers accepted
- No, according to the record
- Phase
- Phase3
- Study record last updated
- 16 April 2026
- Study team last verified status
- 2026-04
These fields are a starting point. Eligibility can include diagnosis, treatment history and other criteria shown only in the complete source record. A registry entry does not establish treatment effectiveness.
England study locations
A location is reproduced as named in the study record. A source map point can represent a town; it is not used here as a hospital entrance or to identify a care provider.
| Location in the source | Local recruitment status | Geographic connection |
|---|---|---|
| Addenbrooke's Hospital Cambridge · CB2 0QQ | Recruiting | Care in Cambridge England postcode |
| Clatterbridge Cancer Centre - Liverpool Liverpool · L7 8YA | Recruiting | Care in Liverpool England postcode |
| The Christie NHS Foundation Trust Manchester · M20 4BX | Recruiting | Care in Manchester England postcode |
| The Royal Marsden in Sutton, Surrey Sutton · SM2 5PT | Recruiting | Care in Sutton England postcode |
| Royal Victoria Infirmary Newcastle upon Tyne · NE1 4LP | Recruiting | Care in Newcastle upon Tyne England postcode |
| Freeman Hospital Newcastle upon Tyne · NE7 7DN | Recruiting | Care in Newcastle upon Tyne England postcode |
| St James University Hospital Leeds · LS9 7TF | Recruiting | Care in Leeds England postcode |
| The Leeds Teaching Hospitals NHS Trust, Leeds General Infimary Leeds · LS1 3EX | Recruiting | Care in Leeds England postcode |
| Guy's Hospital London · SE19RT | Recruiting | Care in Southwark England postcode |
| Churchill Hospital Oxford · Ox3 7LE | Recruiting | Care in Oxford England postcode |
Questions for the research team
- Is this exact location currently enrolling participants, and do my circumstances meet the full criteria?
- What visits, tests, possible risks and follow-up would participation involve?
- Are travel costs or accessibility arrangements available?
- How would participation affect my usual care, and what happens if I withdraw?
Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).
Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.
How we selected and connected these records
Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.