NCT04613596
Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7
Registered research study with 7 identifiable England locations. See source dates, location-specific recruitment and the original study record.
Study facts
- Conditions recorded
- Advanced Non-Small Cell Lung Cancer; Metastatic Non-Small Cell Lung Cancer
- Lead sponsor
- Mirati Therapeutics Inc.
- Study type
- Interventional
- Overall status
- Recruiting · this can differ by location
- Age range in the record
- 18 Years to Not specified
- Sex eligibility field
- All
- Healthy volunteers accepted
- No, according to the record
- Phase
- Phase2, Phase3
- Study record last updated
- 25 August 2026
- Study team last verified status
- 2026-08
These fields are a starting point. Eligibility can include diagnosis, treatment history and other criteria shown only in the complete source record. A registry entry does not establish treatment effectiveness.
England study locations
A location is reproduced as named in the study record. A source map point can represent a town; it is not used here as a hospital entrance or to identify a care provider.
| Location in the source | Local recruitment status | Geographic connection |
|---|---|---|
| University Hospitals Birmingham NHS Foundation Trust Birmingham · B9 5SS | Recruiting | Care in Birmingham England postcode |
| Local Institution - 007-403 Kent · ME16 9QQ | Not yet recruiting | Care in Maidstone England postcode |
| University Hospitals of Leicester NHS Trust Leicester · LE1 5WW | Recruiting | Care in Leicester England postcode |
| University College London Hospitals NHS Foundation Trust London · NW1 2BU | Recruiting | Care in Camden England postcode |
| Guys and St Thomas NHS Foundation Trust London · SE1 9RT | Recruiting | Care in Southwark England postcode |
| The Christie NHS Foundation Trust Manchester · M20 4BX | Recruiting | Care in Manchester England postcode |
| Royal Surrey County Hospital NHS Foundation Trust Surrey · GU2 7XX | Recruiting | Care in Guildford England postcode |
Questions for the research team
- Is this exact location currently enrolling participants, and do my circumstances meet the full criteria?
- What visits, tests, possible risks and follow-up would participation involve?
- Are travel costs or accessibility arrangements available?
- How would participation affect my usual care, and what happens if I withdraw?
Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).
Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.
How we selected and connected these records
Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.