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NCT04389632

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

Registered research study with 9 identifiable England locations. See source dates, location-specific recruitment and the original study record.

Study facts

Conditions recorded
Carcinoma, Non-Small Cell Lung; Squamous Cell Carcinoma of Head and Neck; HER2 Negative Breast Neoplasms; Esophageal Squamous Cell Carcinoma; Esophageal Adenocarcinoma; Gastroesophageal Junction Adenocarcinoma; Ovarian Neoplasms; Cutaneous Squamous Cell Cancer; Exocrine Pancreatic Adenocarcinoma; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Stomach Neoplasms
Lead sponsor
Seagen, a wholly owned subsidiary of Pfizer
Study type
Interventional
Overall status
Recruiting · this can differ by location
Age range in the record
18 Years to Not specified
Sex eligibility field
All
Healthy volunteers accepted
No, according to the record
Phase
Phase1
Study record last updated
6 July 2026
Study team last verified status
2026-07

These fields are a starting point. Eligibility can include diagnosis, treatment history and other criteria shown only in the complete source record. A registry entry does not establish treatment effectiveness.

England study locations

A location is reproduced as named in the study record. A source map point can represent a town; it is not used here as a hospital entrance or to identify a care provider.

Location in the sourceLocal recruitment statusGeographic connection
The Royal Marsden Hospital (Surrey)

Sutton · SM2 5PT

RecruitingCare in Sutton

England postcode

Royal Marsden Hospital

Sutton · SM2 5PT

RecruitingCare in Sutton

England postcode

Queen Elizabeth Hospital

Birmingham · B15 2TH

RecruitingCare in Birmingham

England postcode

University Hospitals Birmingham NHS Foundation Trust

Birmingham · B15 2TH

RecruitingCare in Birmingham

England postcode

The Royal Marsden NHS Foundation Trust

London · SW3 6JJ

RecruitingCare in Kensington and Chelsea

England postcode

Sarah Cannon Research Institute

London · W1G 6AD

RecruitingCare in Westminster

England postcode

Diagnostic centre

London · W1G 7AF

RecruitingCare in Westminster

England postcode

The Harley Street Clinic

London · W1G 8BJ

RecruitingCare in Westminster

England postcode

Radiology

London · W1G 8PP

RecruitingCare in Westminster

England postcode

Questions for the research team

  • Is this exact location currently enrolling participants, and do my circumstances meet the full criteria?
  • What visits, tests, possible risks and follow-up would participation involve?
  • Are travel costs or accessibility arrangements available?
  • How would participation affect my usual care, and what happens if I withdraw?

Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).

Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.

How we selected and connected these records

Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.