NCT04116502 · MITHRIDATE
MITHRIDATE: Ruxolitinib Versus Hydroxycarbamide or Interferon as First Line Therapy in High Risk Polycythemia Vera
Registered research study with 40 identifiable England locations. See source dates, location-specific recruitment and the original study record.
Study facts
- Conditions recorded
- Polycythemia Vera
- Lead sponsor
- University of Birmingham
- Study type
- Interventional
- Overall status
- Recruiting · this can differ by location
- Age range in the record
- 18 Years to Not specified
- Sex eligibility field
- All
- Healthy volunteers accepted
- No, according to the record
- Phase
- Phase3
- Study record last updated
- 28 April 2026
- Study team last verified status
- 2026-04
These fields are a starting point. Eligibility can include diagnosis, treatment history and other criteria shown only in the complete source record. A registry entry does not establish treatment effectiveness.
England study locations
A location is reproduced as named in the study record. A source map point can represent a town; it is not used here as a hospital entrance or to identify a care provider.
| Location in the source | Local recruitment status | Geographic connection |
|---|---|---|
| Royal United Hospital Bath · BA1 3NG | Recruiting | Care in Bath and North East Somerset England postcode |
| Birmingham Heartlands Hospital Birmingham · B9 5SS | Recruiting | Care in Birmingham England postcode |
| Blackpool Victoria Hospital Blackpool · FY3 8NR | Recruiting | Care in Blackpool England postcode |
| Royal Bournemouth Hospital Bournemouth · BH7 7DW | Recruiting | Care in Bournemouth, Christchurch and Poole England postcode |
| Southmead Hospital Bristol · BS10 5NB | Recruiting | Care in Bristol England postcode |
| Addenbrooke's Hospital Cambridge · CB2 0QQ | Recruiting | Care in Cambridge England postcode |
| Kent and Canterbury Hospital Canterbury · CT1 3NG | Recruiting | Care in Canterbury England postcode |
| St Richard's Hospital Chichester · PO19 6SE | Recruiting | Care in Chichester England postcode |
| Colchester Hospital Colchester · CO4 5JL | Recruiting | Care in Colchester England postcode |
| Castle Hill Hospital Cottingham · HU16 5JQ | Recruiting | Care in East Riding of Yorkshire England postcode |
| Russells Hall Hospital Dudley · DY1 2HQ | Recruiting | Care in Dudley England postcode |
| Royal Devon and Exeter Hospital Exeter · EX2 5DW | Recruiting | Care in Exeter England postcode |
| Gloucestershire Royal Hospital Gloucester · GL1 3NN | Recruiting | Care in Gloucester England postcode |
| Calderdale Royal Hospital Halifax · HX3 0PW | Active not recruiting | Care in Calderdale England postcode |
| Huddersfield Royal Infirmary Huddersfield · HD3 3EA | Active not recruiting | Care in Kirklees England postcode |
| Kettering General Hospital Kettering · NN16 8UZ | Recruiting | Care in North Northamptonshire England postcode |
| Leicester Royal Infirmary Leicester · LE1 5WW | Recruiting | Care in Leicester England postcode |
| University College Hospital London · NW1 2BU | Recruiting | Care in Camden England postcode |
| Guy's Hospital London · SE1 9RT | Recruiting | Care in Southwark England postcode |
| St George's Hospital London · SW17 0QT | Recruiting | Care in Wandsworth England postcode |
| Wythenshawe Hospital Manchester · M23 9LT | Recruiting | Care in Manchester England postcode |
| Arrowe Park Hospital Metropolitan Borough of Wirral · CH49 5PE | Recruiting | Care in Wirral England postcode |
| The James Cook University Hospital Middlesbrough · TS4 3BW | Recruiting | Care in Middlesbrough England postcode |
| Freeman Hospital Newcastle upon Tyne · NE7 7DN | Recruiting | Care in Newcastle upon Tyne England postcode |
| North Tyneside General Hospital North Shields · NE29 8NH | Recruiting | Care in North Tyneside England postcode |
| Northampton General Hospital Northampton · NN1 5BD | Recruiting | Care in West Northamptonshire England postcode |
| Norfolk and Norwich University Hospital Norwich · NR4 7UY | Recruiting | Care in South Norfolk England postcode |
| Nottingham City Hospital Nottingham · NG5 1PB | Recruiting | Care in Nottingham England postcode |
| Churchill Hospital Oxford · OX3 7LE | Recruiting | Care in Oxford England postcode |
| Royal Berkshire Hospital Reading · RG1 5AN | Recruiting | Care in Reading England postcode |
| Halton Hospital Runcorn · WA7 2DA | Recruiting | Care in Halton England postcode |
| Wexham Park Hospital Slough · SL2 4HL | Recruiting | Care in Slough England postcode |
| Southampton General Hospital Southampton · SO16 6YD | Recruiting | Care in Southampton England postcode |
| Royal Stoke University Hospital Stoke-on-Trent · ST4 6QG | Recruiting | Care in Stoke-on-Trent England postcode |
| Sunderland Royal Hospital Sunderland · SR4 7TP | Recruiting | Care in Sunderland England postcode |
| Good Hope Hospital Sutton Coldfield · B75 7RR | Recruiting | Care in Birmingham England postcode |
| Royal Cornwall Hospital Truro · TR1 3LJ | Recruiting | Care in Cornwall England postcode |
| Warwick Hospital Warwick · CV34 5BW | Recruiting | Care in Warwick England postcode |
| New Cross Hospital Wolverhampton · WV10 0QP | Recruiting | Care in Wolverhampton England postcode |
| Worthing Hospital Worthing · BN11 2DH | Recruiting | Care in Worthing England postcode |
Questions for the research team
- Is this exact location currently enrolling participants, and do my circumstances meet the full criteria?
- What visits, tests, possible risks and follow-up would participation involve?
- Are travel costs or accessibility arrangements available?
- How would participation affect my usual care, and what happens if I withdraw?
Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).
Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.
How we selected and connected these records
Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.