NCT03486873
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
Registered research study with 15 identifiable England locations. See source dates, location-specific recruitment and the original study record.
Study facts
- Conditions recorded
- Solid Tumors; Hematologic Malignancies
- Lead sponsor
- Merck Sharp & Dohme LLC
- Study type
- Interventional
- Overall status
- Recruiting · this can differ by location
- Age range in the record
- 18 Years to Not specified
- Sex eligibility field
- All
- Healthy volunteers accepted
- No, according to the record
- Phase
- Phase3
- Study record last updated
- 10 September 2026
- Study team last verified status
- 2026-09
These fields are a starting point. Eligibility can include diagnosis, treatment history and other criteria shown only in the complete source record. A registry entry does not establish treatment effectiveness.
England study locations
A location is reproduced as named in the study record. A source map point can represent a town; it is not used here as a hospital entrance or to identify a care provider.
| Location in the source | Local recruitment status | Geographic connection |
|---|---|---|
| Addenbrookes Hospital ( Site 0522) Cambridge · CB2 2QQ | Active not recruiting | England location Source location point within ONS England boundary |
| The Christie ( Site 0516) Manchester · M20 4BX | Recruiting | Care in Manchester England postcode |
| Weston Park Hospital ( Site 0519) Sheffield · S10 2SJ | Recruiting | Care in Sheffield England postcode |
| Mid Essex Hospitals Service Trust. Broomfield Hospital ( Site 0503) Broomfield · CM1 7ET | Completed | Care in Chelmsford England postcode |
| Royal Preston Hospital ( Site 0518) Preston · PR2 9HT | Recruiting | Care in Preston England postcode |
| Barts Health NHS Trust ( Site 0512) London · EC1A 7BE | Recruiting | Care in City of London England postcode |
| University College London Hospital-Cancer Clinical Trials Unit ( Site 0520) London · NW1 2PG | Recruiting | Care in Camden England postcode |
| Royal Free Hospital ( Site 0507) London · NW3 2QG | Active not recruiting | Care in Camden England postcode |
| Royal Marsden Hospital ( Site 0505) London · SW3 6JJ | Recruiting | Care in Kensington and Chelsea England postcode |
| Sarah Cannon Research UK ( Site 0504) London · W1G 6AD | Completed | Care in Westminster England postcode |
| Nottingham University Hospitals NHS Trust ( Site 0510) Nottingham · NG5 1PB | Active not recruiting | Care in Nottingham England postcode |
| University Hospital Coventry & Warwickshire ( Site 0524) Coventry · CV2 2DX | Active not recruiting | Care in Coventry England postcode |
| St James University Hospital ( Site 0509) Leeds · LS9 7TF | Recruiting | Care in Leeds England postcode |
| The Royal Marsden NHS Foundation Trust. ( Site 0513) Sutton · SM2 5PT | Recruiting | Care in Sutton England postcode |
| New Cross Hospital-Department of Oncology ( Site 0517) Wolverhampton · WV10 0QP | Active not recruiting | Care in Wolverhampton England postcode |
Questions for the research team
- Is this exact location currently enrolling participants, and do my circumstances meet the full criteria?
- What visits, tests, possible risks and follow-up would participation involve?
- Are travel costs or accessibility arrangements available?
- How would participation affect my usual care, and what happens if I withdraw?
Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).
Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.
How we selected and connected these records
Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.