NCT05655156 · Interventional
OrthoPureXT Multiligament PMCF Study
Multiligament Knee Injuries
Study overall: Recruiting · source record updated 15 April 2025.
1 England locations · 1 explicitly recorded as recruiting.
RESEARCH IN ENGLAND
Explore clinical trials with England locations
Search 2,970 registered studies with identifiable England locations in our dated ClinicalTrials.gov snapshot. Explore the study and local recruitment details before contacting the research team.
2,970 matching studies · ordered by study identifier.
NCT05656469 · Interventional
Clinical Study Evaluating Pharmacogenomics-informed Pharmacotherapy Versus Dosing as Usual in Psychiatric Disorders
Mood Disorders · Anxiety Disorders · Psychotic Disorders
Study overall: Recruiting · source record updated 2 June 2026.
1 England locations · 1 explicitly recorded as recruiting.
NCT05658497 · Observational
Pregnancy Exposure Registry for Vumerity (Diroximel Fumarate)
Multiple Sclerosis
Study overall: Recruiting · source record updated 11 August 2026.
1 England locations · 1 explicitly recorded as recruiting.
NCT05658640 · Interventional
HEM iSMART-D: Trametinib + Dexamethasone + Chemotherapy in Children With Relapsed or Refractory Hematological Malignancies
Acute Lymphoblastic Leukemia, in Relapse · Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent · Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent · Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory · Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory
Study overall: Recruiting · source record updated 16 September 2025.
5 England locations · 0 explicitly recorded as recruiting.
NCT05659901 · Observational
Rocket Study: A Study to Characterize Biomarkers and Disease Progression in Participants With Pelizaeus-Merzbacher Disease
Pelizaeus-Merzbacher Disease
Study overall: Recruiting · source record updated 17 April 2026.
1 England locations · 1 explicitly recorded as recruiting.
NCT05660642 · Interventional
An Open-Label Study to Evaluate the Safety, Tolerability and Pharmacodynamics of BPL-003 in Patients With Treatment Resistant Depression
Treatment Resistant Depression
Study overall: Recruiting · source record updated 6 July 2026.
3 England locations · 2 explicitly recorded as recruiting.
NCT05661032 · Observational
Novel Technologies for Respiratory Virus Identification
Infections, Respiratory · Respiratory Tract Infections
Study overall: Recruiting · source record updated 30 June 2026.
1 England locations · 1 explicitly recorded as recruiting.
NCT05662111 · Interventional
Treatment of Ectopic Calcification in Fahr's Disease or Syndrome
Fahr Disease · Fahr Syndrome · Primary Familial Brain Calcification
Study overall: Recruiting · source record updated 2 March 2026.
1 England locations · 0 explicitly recorded as recruiting.
NCT05663515 · Observational
A Pan-European Post-Authorisation Safety Study: Risk of Pancreatic Cancer Among Type 2 Diabetes Patients Who Initiated Exenatide as Compared With Those Who Initiated Other Non-Glucagon-Like Peptide 1 Receptor Agonists Based Glucose Lowering Drugs
Pancreatic Cancer
Study overall: Recruiting · source record updated 4 August 2026.
1 England locations · 1 explicitly recorded as recruiting.
NCT05664854 · Interventional
Electrical Impedance Tomography & Selective Stimulation of Vagus Nerve
Vagus Nerve Diseases · Epilepsy · Vagus Nerve Autonomic Disorder
Study overall: Recruiting · source record updated 27 May 2026.
1 England locations · 1 explicitly recorded as recruiting.
NCT05665608 · Interventional
Prevention Of Sudden Cardiac Death After Myocardial Infarction by Defibrillator Implantation
Sudden Cardiac Death · Myocardial Infarction
Study overall: Recruiting · source record updated 1 April 2026.
6 England locations · 6 explicitly recorded as recruiting.
NCT05667142 · Interventional
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
Primary Generalized Tonic-Clonic Seizures
Study overall: Recruiting · source record updated 10 August 2026.
5 England locations · 5 explicitly recorded as recruiting.
NCT05669950 · Interventional
A Trial of Lu AG13909 in Participants With Congenital Adrenal Hyperplasia
Congenital Adrenal Hyperplasia
Study overall: Recruiting · source record updated 9 March 2026.
4 England locations · 4 explicitly recorded as recruiting.
NCT05673499 · Observational
International Study of Cerebral Oxygenation and Electrical Activity During Major Neonatal Surgery
Congenital Disorders · Cerebral Desaturation · Neonatal Surgery
Study overall: Recruiting · source record updated 23 April 2026.
1 England locations · 0 explicitly recorded as recruiting.
NCT05676775 · Observational
British Axial Spondyloarthritis Inception Cohort
Axial Spondyloarthritis
Study overall: Recruiting · source record updated 18 July 2023.
1 England locations · 1 explicitly recorded as recruiting.
NCT05677971 · Interventional
Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein
Alpha1-Antitrypsin Deficiency
Study overall: Recruiting · source record updated 13 May 2026.
5 England locations · 4 explicitly recorded as recruiting.
NCT05681754 · Interventional
Endo-perio Disease - Treatment Outcomes Using Conventional and Hydraulic Calcium Silicate Sealer With or Without LPRF
Endodontic Disease · Periodontitis
Study overall: Not yet recruiting · source record updated 12 January 2023.
1 England locations · 0 explicitly recorded as recruiting.
NCT05682378 · Interventional
Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION-16, ORION-13, ORION-20, or ORION-19 Studies
Heterozygous or Homozygous Familial Hypercholesterolemia
Study overall: Recruiting · source record updated 15 May 2026.
1 England locations · 0 explicitly recorded as recruiting.
NCT05683093 · Observational
Cardiovascular Longitudinal ALSPAC Research Investigations Following Hypertensive Pregnancy in Young Adulthood
Young Adult · Hypertension in Pregnancy · Hypertension · Cardiovascular Diseases · Cerebrovascular Diseases · Vascular Diseases
Study overall: Recruiting · source record updated 12 January 2023.
1 England locations · 1 explicitly recorded as recruiting.
NCT05685173 · Interventional
A Trial to Study if REGN5837 in Combination With Odronextamab is Safe for Adult Participants With Aggressive B-cell Non-Hodgkin Lymphomas
B-cell Non-Hodgkins Lymphoma (B-NHL)
Study overall: Recruiting · source record updated 19 May 2026.
3 England locations · 3 explicitly recorded as recruiting.
More ways to explore research
This is a selected international registry feed, not every study taking place in England. NIHR also lists participation opportunities, including studies that may not appear in this selection.
Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).
Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.
How we selected and connected these records
Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.