NCT06265727 · Interventional
A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors
Solid Tumor, Adult
Study overall: Recruiting · source record updated 8 January 2026.
8 England locations · 8 explicitly recorded as recruiting.
RESEARCH IN ENGLAND
Explore clinical trials with England locations
Search 2,970 registered studies with identifiable England locations in our dated ClinicalTrials.gov snapshot. Explore the study and local recruitment details before contacting the research team.
54 matching studies · ordered by study identifier.
The area filter uses exact source postcodes. Locations without a matched postcode remain in the England-wide results.
NCT06472245 · Interventional
Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor
Patients With Non-Small Cell Lung Cancer
Study overall: Recruiting · source record updated 23 July 2026.
4 England locations · 4 explicitly recorded as recruiting.
NCT06531824 · Interventional
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)
Kidney Disease, Chronic
Study overall: Recruiting · source record updated 2 September 2026.
58 England locations · 58 explicitly recorded as recruiting.
NCT06561386 · Interventional
A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%
Non-small Cell Lung Cancer
Study overall: Recruiting · source record updated 17 August 2026.
9 England locations · 4 explicitly recorded as recruiting.
NCT06603844 · Interventional
First-in-human Study of CRB-601-01 to Treat Patients With Advanced Solid Tumor.
Solid Tumor
Study overall: Recruiting · source record updated 3 June 2025.
4 England locations · 0 explicitly recorded as recruiting.
NCT06623422 · Interventional
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
Carcinoma, Non-Small-Cell Lung
Study overall: Recruiting · source record updated 27 August 2026.
12 England locations · 12 explicitly recorded as recruiting.
NCT06629779 · Interventional
A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.
Metastatic Castration-Resistant Prostate Cancer
Study overall: Recruiting · source record updated 24 August 2026.
4 England locations · 4 explicitly recorded as recruiting.
NCT06646276 · Interventional
A Study to Compare the Efficacy and Safety of BMS-986489 (BMS-986012+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).
Extensive-Stage Small Cell Lung Cancer
Study overall: Recruiting · source record updated 31 August 2026.
3 England locations · 0 explicitly recorded as recruiting.
NCT06742996 · Interventional
A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)
Mantle Cell Lymphoma · B Cell Lymphoma
Study overall: Recruiting · source record updated 19 August 2026.
6 England locations · 6 explicitly recorded as recruiting.
NCT06792695 · Interventional
A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer
Metastatic Colorectal Cancer
Study overall: Recruiting · source record updated 18 August 2026.
5 England locations · 5 explicitly recorded as recruiting.
NCT06803771 · Interventional
Surveillance of Pancreatic Health After Diabetes Diagnosis
Diabetes Mellitus · Pancreatic Cancer, Adult
Study overall: Recruiting · source record updated 23 March 2026.
31 England locations · 31 explicitly recorded as recruiting.
NCT06897475 · Interventional
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
Type 2 Diabetes
Study overall: Recruiting · source record updated 21 August 2026.
10 England locations · 10 explicitly recorded as recruiting.
NCT06943872 · Interventional
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
Chronic Lymphocytic Leukemia · Small Lymphocytic Lymphoma
Study overall: Recruiting · source record updated 24 August 2026.
7 England locations · 7 explicitly recorded as recruiting.
NCT06988475 · Interventional
DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations
Solid Tumour · Haematological Malignancy · Malignant Neoplasm · Neoplasms by Histologic Type · Neoplasms by Site · Cancer · Malignancy · Glioma · Neuroblastoma · Gastric Cancer · Soft Tissue Sarcoma
Study overall: Recruiting · source record updated 24 November 2025.
13 England locations · 12 explicitly recorded as recruiting.
NCT06988605 · Observational
Real-world Experience Using Nemolizumab in the Treatment of Moderate-to-Severe Atopic Dermatitis in Adolescents & Adults
Atopic Dermatitis
Study overall: Recruiting · source record updated 13 March 2026.
21 England locations · 21 explicitly recorded as recruiting.
NCT07000357 · Interventional
A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event
Cardiovascular Disease
Study overall: Recruiting · source record updated 24 August 2026.
31 England locations · 31 explicitly recorded as recruiting.
NCT07015190 · Interventional
Neoadjuvant Darovasertib in Primary Uveal Melanoma
Uveal Melanoma
Study overall: Recruiting · source record updated 6 May 2026.
3 England locations · 0 explicitly recorded as recruiting.
NCT07043400 · Interventional
A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
Metastatic Gastric Adenocarcinoma · Gastroesophageal Junction Adenocarcinoma
Study overall: Recruiting · source record updated 24 August 2026.
2 England locations · 2 explicitly recorded as recruiting.
NCT07044336 · Interventional
Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)
Endometrial Cancer · Malignant Solid Tumour
Study overall: Recruiting · source record updated 29 July 2026.
9 England locations · 6 explicitly recorded as recruiting.
NCT07064473 · Interventional
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Diabetes Mellitus, Type 2 · Hypertension · Cardiovascular Diseases
Study overall: Recruiting · source record updated 3 September 2026.
30 England locations · 30 explicitly recorded as recruiting.
More ways to explore research
This is a selected international registry feed, not every study taking place in England. NIHR also lists participation opportunities, including studies that may not appear in this selection.
Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).
Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.
How we selected and connected these records
Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.