RESEARCH IN ENGLAND

Explore clinical trials with England locations

Search 2,970 registered studies with identifiable England locations in our dated ClinicalTrials.gov snapshot. Explore the study and local recruitment details before contacting the research team.

Condition, study or locationRecorded care areaStatus at an England locationClear filters

194 matching studies · ordered by study identifier.

The area filter uses exact source postcodes. Locations without a matched postcode remain in the England-wide results.

NCT06129864 · Interventional

A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy

Locally Advanced Head and Neck Squamous Cell Carcinoma

Study overall: Recruiting · source record updated 3 September 2026.

11 England locations · 9 explicitly recorded as recruiting.

NCT06137118 · Interventional

AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia

B-cell Acute Lymphoblastic Leukemia (B-ALL)

Study overall: Recruiting · source record updated 19 August 2026.

3 England locations · 0 explicitly recorded as recruiting.

NCT06149286 · Interventional

A Trial to Find Out if Odronextamab Combined With Lenalidomide is Safe and Works Better Than Rituximab Combined With Lenalidomide in Adult Participants With Follicular Lymphoma and Marginal Zone Lymphoma

Relapsed/Refractory Follicular Lymphoma · Relapsed/Refractory Marginal Zone Lymphoma (R/R MZL)

Study overall: Recruiting · source record updated 14 August 2026.

9 England locations · 9 explicitly recorded as recruiting.

NCT06152575 · Interventional

MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)

Multiple Myeloma

Study overall: Recruiting · source record updated 24 August 2026.

16 England locations · 16 explicitly recorded as recruiting.

NCT06190899 · Interventional

Gedatolisib in Combination With Darolutamide in Metastatic Castration-Resistant Prostate Cancer

mCRPC (Metastatic Castration-resistant Prostate Cancer) · Genital Diseases, Male · Urogenital Diseases, Male · Prostatic Disease · Prostatic Neoplasms, Castration-Resistant · Prostate Cancer

Study overall: Recruiting · source record updated 13 April 2026.

3 England locations · 1 explicitly recorded as recruiting.

NCT06216301 · Interventional

LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC

Metastatic Non-small Cell Lung Cancer

Study overall: Recruiting · source record updated 25 June 2026.

5 England locations · 5 explicitly recorded as recruiting.

NCT06217822 · Interventional

First-in-human Study of 225Ac-PSMA-Trillium (BAY 3563254) in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)

Advanced Metastatic Castration-resistant Prostate Cancer · Prostate Specific Membrane Antigen (PSMA) Expression

Study overall: Recruiting · source record updated 7 July 2026.

3 England locations · 2 explicitly recorded as recruiting.

NCT06242470 · Interventional

A Study of MGC026 in Participants With Advanced Solid Tumors

Advanced Solid Tumor · Advanced Cancer · Metastatic Cancer · Squamous Cell Carcinoma of Head and Neck · Non Small Cell Lung Cancer · Small-cell Lung Cancer · Bladder Cancer · Sarcoma · Endometrial Cancer · Melanoma · Castration Resistant Prostatic Cancer · Cervical Cancer · Colorectal Cancer · Gastric Cancer · Gastro-esophageal Cancer · Pancreas Cancer · Clear Cell Renal Cell Carcinoma · Hepatocellular Carcinoma · Platinum-resistant Ovarian Cancer · Breast Cancer · Ovarian Cancer · Esophageal Squamous Cell Cancer (SCC)

Study overall: Recruiting · source record updated 11 August 2026.

2 England locations · 2 explicitly recorded as recruiting.

NCT06252649 · Interventional

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

Metastatic Colorectal Cancer

Study overall: Recruiting · source record updated 3 September 2026.

9 England locations · 9 explicitly recorded as recruiting.

NCT06253871 · Interventional

A Phase 1/1b Study of IAM1363 in HER2 Cancers

HER2 Mutation-Related Tumors · HER2 · HER2-positive Breast Cancer · HER2 + Breast Cancer · Brain Metastases From Solid Tumors · Brain Metastases From HER2 and Breast Cancer · CNS Metastases · HER2-Positive Solid Tumors · NSCLC (Non-small Cell Lung Cancer) · HER2-positive Bladder Cancer · HER2-positive Colorectal Cancer · HER2 + Gastric Cancer · HER2-positive Gastroesophageal Cancer

Study overall: Recruiting · source record updated 9 September 2026.

3 England locations · 3 explicitly recorded as recruiting.

NCT06256588 · Interventional

A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma

Neoplasms, Head and Neck

Study overall: Recruiting · source record updated 26 May 2026.

5 England locations · 4 explicitly recorded as recruiting.

NCT06282575 · Interventional

Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer

Biliary Tract Cancer

Study overall: Recruiting · source record updated 14 July 2026.

4 England locations · 4 explicitly recorded as recruiting.

NCT06319820 · Interventional

A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer

Non-Muscle Invasive Bladder Neoplasms

Study overall: Recruiting · source record updated 28 August 2026.

7 England locations · 7 explicitly recorded as recruiting.

NCT06320067 · Interventional

A Randomised Controlled Platform Trial Testing Treatments in Metastatic Hormone Sensitive Prostate Cancer

Prostate Cancer Metastatic

Study overall: Recruiting · source record updated 26 September 2025.

18 England locations · 18 explicitly recorded as recruiting.

NCT06324357 · Interventional

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

Metastatic Breast Cancer · Metastatic Gastric Adenocarcinoma · Gastroesophageal Junction Adenocarcinoma · Esophageal Adenocarcinoma · Colorectal Cancer

Study overall: Recruiting · source record updated 6 August 2026.

9 England locations · 7 explicitly recorded as recruiting.

NCT06372717 · Interventional

A Study to Investigate APL-4098 Alone and in Combination in Adults With AML or MDS

Acute Myeloid Leukemia Refractory · Myelodysplastic Syndrome Acute Myeloid Leukemia · Myelodysplastic Syndrome With Excess Blasts · Acute Myeloid Leukemia, in Relapse · Acute Myeloid Leukemia (AML)

Study overall: Recruiting · source record updated 1 June 2026.

2 England locations · 2 explicitly recorded as recruiting.

NCT06385080 · Interventional

A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer

Squamous Cell Carcinoma of Head and Neck

Study overall: Recruiting · source record updated 28 August 2026.

7 England locations · 6 explicitly recorded as recruiting.

NCT06395103 · Interventional

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

B-cell Acute Lymphoblastic Leukemia · Diffuse Large B-cell Lymphoma · Burkitt Lymphoma · Neuroblastoma · Ewing Sarcoma

Study overall: Recruiting · source record updated 3 September 2026.

4 England locations · 4 explicitly recorded as recruiting.

NCT06402201 · Interventional

First in Human Study of CDR404 in HLA-A*02:01 Participants With MAGE-A4 Expressing Solid Tumors

Select Advanced Solid Tumors

Study overall: Recruiting · source record updated 27 February 2026.

1 England locations · 1 explicitly recorded as recruiting.

NCT06423976 · Observational

Microbiome Molecular Charaterisation

Prostate Cancer

Study overall: Recruiting · source record updated 24 May 2024.

1 England locations · 1 explicitly recorded as recruiting.

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This is a selected international registry feed, not every study taking place in England. NIHR also lists participation opportunities, including studies that may not appear in this selection.

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Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).

Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.

How we selected and connected these records

Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.