RESEARCH IN ENGLAND

Explore clinical trials with England locations

Search 2,970 registered studies with identifiable England locations in our dated ClinicalTrials.gov snapshot. Explore the study and local recruitment details before contacting the research team.

Condition, study or locationRecorded care areaStatus at an England locationClear filters

208 matching studies · ordered by study identifier.

The area filter uses exact source postcodes. Locations without a matched postcode remain in the England-wide results.

NCT06963021 · Interventional

NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

Major Depressive Disorder

Study overall: Recruiting · source record updated 10 August 2026.

4 England locations · 4 explicitly recorded as recruiting.

NCT06963827 · Interventional

A Study of Mezagitamab in Adults With Kidney Condition Called IgA Nephropathy

Kidney Disease

Study overall: Recruiting · source record updated 14 August 2026.

10 England locations · 10 explicitly recorded as recruiting.

NCT06966401 · Interventional

Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

Major Depressive Disorder

Study overall: Recruiting · source record updated 24 July 2026.

4 England locations · 2 explicitly recorded as recruiting.

NCT06976203 · Interventional

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)

Alzheimer's Disease

Study overall: Recruiting · source record updated 12 August 2026.

6 England locations · 6 explicitly recorded as recruiting.

NCT06979323 · Interventional

Depemokimab Asthma Imaging and Bronchoscopy Sub-Study

Asthma

Study overall: Recruiting · source record updated 2 July 2026.

4 England locations · 4 explicitly recorded as recruiting.

NCT06979336 · Interventional

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)

Ulcerative Colitis

Study overall: Recruiting · source record updated 27 August 2026.

5 England locations · 5 explicitly recorded as recruiting.

NCT06979596 · Interventional

A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)

Malignant Neoplasm

Study overall: Recruiting · source record updated 28 August 2026.

7 England locations · 7 explicitly recorded as recruiting.

NCT06988475 · Interventional

DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations

Solid Tumour · Haematological Malignancy · Malignant Neoplasm · Neoplasms by Histologic Type · Neoplasms by Site · Cancer · Malignancy · Glioma · Neuroblastoma · Gastric Cancer · Soft Tissue Sarcoma

Study overall: Recruiting · source record updated 24 November 2025.

13 England locations · 12 explicitly recorded as recruiting.

NCT06988605 · Observational

Real-world Experience Using Nemolizumab in the Treatment of Moderate-to-Severe Atopic Dermatitis in Adolescents & Adults

Atopic Dermatitis

Study overall: Recruiting · source record updated 13 March 2026.

21 England locations · 21 explicitly recorded as recruiting.

NCT06989437 · Interventional

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

Cachexia · Metastatic Pancreatic Ductal Adenocarcinoma

Study overall: Recruiting · source record updated 24 August 2026.

6 England locations · 6 explicitly recorded as recruiting.

NCT07007793 · Interventional

A Study to Assess Efficacy and Safety of Baxdrostat in Participants With Primary Aldosteronism

Primary Hyperaldosteronism

Study overall: Recruiting · source record updated 6 July 2026.

3 England locations · 0 explicitly recorded as recruiting.

NCT07011745 · Interventional

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease

Alzheimer's Disease

Study overall: Recruiting · source record updated 26 August 2026.

9 England locations · 6 explicitly recorded as recruiting.

NCT07013201 · Interventional

A 16-week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream 20 mg/g in Adult Participants With Mild to Severe Palmoplantar Pustulosis

Palmoplantar Pustulosis

Study overall: Recruiting · source record updated 31 August 2026.

5 England locations · 5 explicitly recorded as recruiting.

NCT07016295 · Observational

Monitoring Arm Recovery After Stroke (MARS)

Stroke

Study overall: Recruiting · source record updated 11 August 2025.

1 England locations · 1 explicitly recorded as recruiting.

NCT07018323 · Interventional

A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

Graves' Disease

Study overall: Recruiting · source record updated 25 August 2026.

5 England locations · 5 explicitly recorded as recruiting.

NCT07023627 · Interventional

A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

Ovarian Cancer

Study overall: Recruiting · source record updated 6 August 2026.

4 England locations · 4 explicitly recorded as recruiting.

NCT07028853 · Interventional

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

Metastatic Castration Sensitive Prostate Cancer (mCSPC) · Hormone Sensitive Prostate Cancer · Prostate Cancer · Cancer of the Prostate

Study overall: Recruiting · source record updated 14 August 2026.

8 England locations · 8 explicitly recorded as recruiting.

NCT07079631 · Interventional

A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment Pumitamig (BNT327) and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer

Metastatic Colorectal Cancer

Study overall: Recruiting · source record updated 1 July 2026.

3 England locations · 3 explicitly recorded as recruiting.

NCT07081503 · Interventional

Phase 1 Study of ADX-626 in Healthy Participants

Healthy Adult Participants

Study overall: Recruiting · source record updated 10 September 2026.

1 England locations · 1 explicitly recorded as recruiting.

NCT07094516 · Interventional

A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease

Alzheimer's Disease

Study overall: Recruiting · source record updated 26 June 2026.

7 England locations · 7 explicitly recorded as recruiting.

More ways to explore research

This is a selected international registry feed, not every study taking place in England. NIHR also lists participation opportunities, including studies that may not appear in this selection.

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Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).

Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.

How we selected and connected these records

Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.