NCT06953869 · Interventional
Evaluating the Effects of Tasimelteon vs. Placebo in Treating Pediatric Insomnia
Insomnia Disorder
Study overall: Recruiting · source record updated 5 June 2026.
7 England locations · 7 explicitly recorded as recruiting.
RESEARCH IN ENGLAND
Explore clinical trials with England locations
Search 2,970 registered studies with identifiable England locations in our dated ClinicalTrials.gov snapshot. Explore the study and local recruitment details before contacting the research team.
186 matching studies · ordered by study identifier.
The area filter uses exact source postcodes. Locations without a matched postcode remain in the England-wide results.
NCT06954272 · Observational
Characterisation of Skin Microstructure Under Normal and Atrophied States
Atopic Dermatitis
Study overall: Recruiting · source record updated 1 May 2025.
1 England locations · 1 explicitly recorded as recruiting.
NCT06963021 · Interventional
NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Major Depressive Disorder
Study overall: Recruiting · source record updated 10 August 2026.
4 England locations · 4 explicitly recorded as recruiting.
NCT06966401 · Interventional
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Major Depressive Disorder
Study overall: Recruiting · source record updated 24 July 2026.
4 England locations · 2 explicitly recorded as recruiting.
NCT06976203 · Interventional
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
Alzheimer's Disease
Study overall: Recruiting · source record updated 12 August 2026.
6 England locations · 6 explicitly recorded as recruiting.
NCT06978985 · Observational
Adult SMA Research and Clinical Hub
Spinal Muscular Atrophy (SMA)
Study overall: Recruiting · source record updated 18 May 2025.
15 England locations · 15 explicitly recorded as recruiting.
NCT06988475 · Interventional
DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations
Solid Tumour · Haematological Malignancy · Malignant Neoplasm · Neoplasms by Histologic Type · Neoplasms by Site · Cancer · Malignancy · Glioma · Neuroblastoma · Gastric Cancer · Soft Tissue Sarcoma
Study overall: Recruiting · source record updated 24 November 2025.
13 England locations · 12 explicitly recorded as recruiting.
NCT06988605 · Observational
Real-world Experience Using Nemolizumab in the Treatment of Moderate-to-Severe Atopic Dermatitis in Adolescents & Adults
Atopic Dermatitis
Study overall: Recruiting · source record updated 13 March 2026.
21 England locations · 21 explicitly recorded as recruiting.
NCT07000357 · Interventional
A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event
Cardiovascular Disease
Study overall: Recruiting · source record updated 24 August 2026.
31 England locations · 31 explicitly recorded as recruiting.
NCT07011745 · Interventional
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease
Alzheimer's Disease
Study overall: Recruiting · source record updated 26 August 2026.
9 England locations · 6 explicitly recorded as recruiting.
NCT07049042 · Observational
Hypogonadotrophic Hypogonadism in Genetic Neurodevelopmental Conditions
Genetic Neurodevelopmental Disorders
Study overall: Recruiting · source record updated 3 July 2025.
1 England locations · 1 explicitly recorded as recruiting.
NCT07058077 · Interventional
A Study of Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)
Heterozygous Familial Hypercholesterolemia (HeFH)
Study overall: Recruiting · source record updated 21 August 2026.
3 England locations · 3 explicitly recorded as recruiting.
NCT07071181 · Interventional
Effects of Milk-based Drinks on Gut Microbiome, Sleep and Cardiometabolic Markers
Sleep · Cardiovascular Diseases · Gut Microbiome · Cognitive Function and Mood · LDL Cholesterol
Study overall: Recruiting · source record updated 17 July 2025.
2 England locations · 1 explicitly recorded as recruiting.
NCT07071519 · Interventional
A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis
Ulcerative Colitis
Study overall: Recruiting · source record updated 4 September 2026.
3 England locations · 3 explicitly recorded as recruiting.
NCT07087054 · Interventional
Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen
Carcinoid Syndrome · Carcinoid · Carcinoid Tumor · Carcinoid Tumor of Ileum · Carcinoid Tumor of Cecum · Carcinoid Tumor of Liver · Carcinoid Tumor of Pancreas · Carcinoid Syndrome Diarrhea · Carcinoid Intestine Tumor
Study overall: Recruiting · source record updated 4 August 2026.
6 England locations · 6 explicitly recorded as recruiting.
NCT07088068 · Interventional
A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes
Type 1 Diabetes Mellitus
Study overall: Recruiting · source record updated 9 September 2026.
9 England locations · 9 explicitly recorded as recruiting.
NCT07106762 · Interventional
Phase 2/3 Trial of Izalontamab Brengitecan vs Platinum-based Chemotherapy for Metastatic Urothelial Cancer With Disease Progression on or After Immunotherapy
Urothelial Cancer
Study overall: Recruiting · source record updated 29 July 2026.
3 England locations · 2 explicitly recorded as recruiting.
NCT07124078 · Interventional
A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256)
Chronic Graft-versus-host-disease
Study overall: Recruiting · source record updated 25 August 2026.
8 England locations · 8 explicitly recorded as recruiting.
NCT07130136 · Interventional
Post-market Evaluation of the Transition From the Baha Connect System to the Osia System in Adult Bone Conduction Implant Recipients
Bone Conduction · Hearing Loss, Conductive · Hearing Loss, Mixed
Study overall: Recruiting · source record updated 2 September 2026.
3 England locations · 2 explicitly recorded as recruiting.
NCT07144163 · Interventional
A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia
Congenital Adrenal Hyperplasia · Classic Congenital Adrenal Hyperplasia
Study overall: Recruiting · source record updated 2 September 2026.
3 England locations · 3 explicitly recorded as recruiting.
More ways to explore research
This is a selected international registry feed, not every study taking place in England. NIHR also lists participation opportunities, including studies that may not appear in this selection.
Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).
Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.
How we selected and connected these records
Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.