RESEARCH IN ENGLAND

Explore clinical trials with England locations

Search 2,970 registered studies with identifiable England locations in our dated ClinicalTrials.gov snapshot. Explore the study and local recruitment details before contacting the research team.

Condition, study or locationRecorded care areaStatus at an England locationClear filters

186 matching studies · ordered by study identifier.

The area filter uses exact source postcodes. Locations without a matched postcode remain in the England-wide results.

NCT06424288 · Interventional

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

Heart Failure

Study overall: Recruiting · source record updated 21 August 2026.

10 England locations · 9 explicitly recorded as recruiting.

NCT06435156 · Interventional

Sotagliflozin in Patients With Heart Failure Symptoms and Type 1 Diabetes

Type 1 Diabetes · Heart Failure

Study overall: Recruiting · source record updated 6 April 2026.

12 England locations · 12 explicitly recorded as recruiting.

NCT06439277 · Interventional

A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)

Obesity · Weight Gain

Study overall: Recruiting · source record updated 4 September 2026.

8 England locations · 0 explicitly recorded as recruiting.

NCT06463587 · Interventional

Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

Generalized Myasthenia Gravis

Study overall: Recruiting · source record updated 12 August 2026.

3 England locations · 3 explicitly recorded as recruiting.

NCT06507579 · Observational

Hydra Registry - UK

Aortic Valve Stenosis

Study overall: Recruiting · source record updated 18 August 2026.

3 England locations · 2 explicitly recorded as recruiting.

NCT06511648 · Interventional

Erdafitinib Monotherapy or in Combination With Cetrelimab in Muscle-invasive Bladder Cancer Patients With Fibroblast Growth Factor Receptor (FGFR ) Gene Alterations

Muscle-invasive Bladder Cancer

Study overall: Recruiting · source record updated 19 December 2025.

5 England locations · 4 explicitly recorded as recruiting.

NCT06555419 · Interventional

A Study to Find Out How Nusinersen is Processed in the Body When Given Through the ThecaFlex DRx™ System in Adult and Pediatric Participants With Spinal Muscular Atrophy (PIERRE-PK)

Muscular Atrophy, Spinal

Study overall: Recruiting · source record updated 3 September 2026.

1 England locations · 1 explicitly recorded as recruiting.

NCT06556563 · Interventional

EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma

Glioblastoma

Study overall: Recruiting · source record updated 19 August 2026.

9 England locations · 0 explicitly recorded as recruiting.

NCT06609226 · Interventional

A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia

Sickle Cell Disease · Thalassemia

Study overall: Recruiting · source record updated 13 August 2026.

8 England locations · 6 explicitly recorded as recruiting.

NCT06615479 · Interventional

A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

Relapsed or Refractory Multiple Myeloma (RRMM)

Study overall: Recruiting · source record updated 18 August 2026.

6 England locations · 6 explicitly recorded as recruiting.

NCT06628427 · Observational

Unlock the Secrets of Ageing Brains Through P300 Brain-computer Interface Games

Mild Cognitive Impairment (MCI)

Study overall: Not yet recruiting · source record updated 8 October 2024.

1 England locations · 0 explicitly recorded as recruiting.

NCT06632444 · Interventional

LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis

Metabolic Dysfunction Associated Steatohepatitis (MASH) · Liver Fibrosis

Study overall: Recruiting · source record updated 21 August 2026.

21 England locations · 21 explicitly recorded as recruiting.

NCT06632457 · Interventional

LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis

Metabolic Dysfunction Associated Steatohepatitis

Study overall: Recruiting · source record updated 3 September 2026.

19 England locations · 19 explicitly recorded as recruiting.

NCT06633627 · Observational

Neurological Responses in Patients with Dentine Hypersensitivity

Dentine Hypersensitivity

Study overall: Recruiting · source record updated 9 October 2024.

1 England locations · 1 explicitly recorded as recruiting.

NCT06641466 · Interventional

A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual Migraine

Menstrual Migraine

Study overall: Recruiting · source record updated 9 July 2026.

7 England locations · 7 explicitly recorded as recruiting.

NCT06649110 · Interventional

A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)

Healthy Volunteers, Pulmonary Arterial Hypertension

Study overall: Recruiting · source record updated 21 July 2026.

4 England locations · 4 explicitly recorded as recruiting.

NCT06663332 · Interventional

A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants

Crohns Disease · Colitis, Ulcerative · Arthritis, Psoriatic · Arthritis, Juvenile

Study overall: Recruiting · source record updated 28 August 2026.

3 England locations · 3 explicitly recorded as recruiting.

NCT06712316 · Interventional

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

Non-small Cell Lung Cancer

Study overall: Recruiting · source record updated 4 September 2026.

15 England locations · 15 explicitly recorded as recruiting.

NCT06735248 · Interventional

A Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With Placebo in Participants Aged 18 to ≤55 Years

Multiple Sclerosis

Study overall: Recruiting · source record updated 15 June 2026.

5 England locations · 5 explicitly recorded as recruiting.

NCT06758401 · Interventional

This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.

Non-Small Cell Lung Cancer · Carcinoma, Non-Small-Cell Lung · Carcinoma, Non-Small-Cell Lung (NSCLC)

Study overall: Recruiting · source record updated 22 July 2026.

8 England locations · 4 explicitly recorded as recruiting.

More ways to explore research

This is a selected international registry feed, not every study taking place in England. NIHR also lists participation opportunities, including studies that may not appear in this selection.

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Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).

Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.

How we selected and connected these records

Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.