NCT06603844 · Interventional
First-in-human Study of CRB-601-01 to Treat Patients With Advanced Solid Tumor.
Solid Tumor
Study overall: Recruiting · source record updated 3 June 2025.
4 England locations · 0 explicitly recorded as recruiting.
RESEARCH IN ENGLAND
Explore clinical trials with England locations
Search 2,970 registered studies with identifiable England locations in our dated ClinicalTrials.gov snapshot. Explore the study and local recruitment details before contacting the research team.
208 matching studies · ordered by study identifier.
The area filter uses exact source postcodes. Locations without a matched postcode remain in the England-wide results.
NCT06615479 · Interventional
A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)
Relapsed or Refractory Multiple Myeloma (RRMM)
Study overall: Recruiting · source record updated 18 August 2026.
6 England locations · 6 explicitly recorded as recruiting.
NCT06618287 · Interventional
A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors
Lung Cancer · Breast Cancer
Study overall: Recruiting · source record updated 18 August 2026.
3 England locations · 2 explicitly recorded as recruiting.
NCT06627647 · Interventional
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC
Non-squamous Non-small Cell Lung Cancer
Study overall: Recruiting · source record updated 14 August 2026.
8 England locations · 7 explicitly recorded as recruiting.
NCT06635148 · Interventional
A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
Geographic Atrophy · Macular Degeneration
Study overall: Recruiting · source record updated 6 July 2026.
4 England locations · 0 explicitly recorded as recruiting.
NCT06659445 · Interventional
Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD
Geographic Atrophy (GA) · Age - Related Macular Degeneration (AMD)
Study overall: Recruiting · source record updated 10 September 2026.
7 England locations · 7 explicitly recorded as recruiting.
NCT06660394 · Interventional
A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)
Dravet Syndrome
Study overall: Recruiting · source record updated 10 August 2026.
3 England locations · 3 explicitly recorded as recruiting.
NCT06667453 · Interventional
A Clinical Study of PGN-EDODM1 in People With Myotonic Dystrophy Type 1
Myotonic Dystrophy 1
Study overall: Recruiting · source record updated 29 July 2026.
3 England locations · 3 explicitly recorded as recruiting.
NCT06667700 · Interventional
A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)
Coronavirus Disease (COVID-19)
Study overall: Recruiting · source record updated 9 September 2026.
9 England locations · 9 explicitly recorded as recruiting.
NCT06680830 · Interventional
A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease
Parkinson Disease · Parkinson · Idiopathic Parkinson Disease · Early Parkinson Disease (Early PD) · Parkinson Disease, Idiopathic
Study overall: Recruiting · source record updated 28 August 2026.
5 England locations · 3 explicitly recorded as recruiting.
NCT06692738 · Interventional
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)
Non-small Cell Lung Cancer
Study overall: Recruiting · source record updated 13 August 2026.
8 England locations · 7 explicitly recorded as recruiting.
NCT06712355 · Interventional
Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer
Extensive-stage Small-cell Lung Cancer
Study overall: Recruiting · source record updated 1 September 2026.
16 England locations · 16 explicitly recorded as recruiting.
NCT06717919 · Interventional
HOPE Against Cancer Recurrence in HCC
Liver Transplantation · HCC · Oncological Outcomes
Study overall: Recruiting · source record updated 16 December 2025.
5 England locations · 0 explicitly recorded as recruiting.
NCT06727604 · Interventional
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease
Graves' Disease
Study overall: Recruiting · source record updated 25 August 2026.
12 England locations · 12 explicitly recorded as recruiting.
NCT06735248 · Interventional
A Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With Placebo in Participants Aged 18 to ≤55 Years
Multiple Sclerosis
Study overall: Recruiting · source record updated 15 June 2026.
5 England locations · 5 explicitly recorded as recruiting.
NCT06780774 · Interventional
Investigating the Acute and Chronic Effects of a Supplement Containing Caffeine, Vitamins, Minerals and Botanical Extracts on Cognition, Sleep and Wellbeing, in Healthy Volunteers
Caffeine · Sleep · Cognitive Function · Wellbeing · Mood
Study overall: Not yet recruiting · source record updated 10 February 2025.
1 England locations · 0 explicitly recorded as recruiting.
NCT06793397 · Interventional
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
Major Depressive Disorder (MDD) · Depression in Adults · Depression - Major Depressive Disorder · Depression Disorders · Depression Disorder · Depression
Study overall: Recruiting · source record updated 26 August 2026.
10 England locations · 9 explicitly recorded as recruiting.
NCT06819878 · Interventional
A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
Moderately to Severely Active Crohns Disease
Study overall: Recruiting · source record updated 20 August 2026.
8 England locations · 7 explicitly recorded as recruiting.
NCT06830759 · Observational
Real-World Study to Assess Subcutaneous Epcoritamab in Adult Participants With Diffuse Large B-Cell and Follicular Lymphoma
Diffuse Large B-cell Lymphoma · Follicular Lymphoma
Study overall: Recruiting · source record updated 17 February 2026.
7 England locations · 7 explicitly recorded as recruiting.
NCT06844214 · Interventional
A Study to Investigate the Safety, Tolerability, and Efficacy of SAR446268, an Adeno-associated Viral Vector-mediated Gene Therapy in Participants Aged 10 to 55 Years of Age With Non-congenital Myotonic Dystrophy Type 1
Myotonic Dystrophy
Study overall: Recruiting · source record updated 1 June 2026.
1 England locations · 1 explicitly recorded as recruiting.
More ways to explore research
This is a selected international registry feed, not every study taking place in England. NIHR also lists participation opportunities, including studies that may not appear in this selection.
Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).
Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.
How we selected and connected these records
Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.