RESEARCH IN ENGLAND

Explore clinical trials with England locations

Search 2,970 registered studies with identifiable England locations in our dated ClinicalTrials.gov snapshot. Explore the study and local recruitment details before contacting the research team.

Condition, study or locationRecorded care areaStatus at an England locationClear filters

421 matching studies · ordered by study identifier.

The area filter uses exact source postcodes. Locations without a matched postcode remain in the England-wide results.

NCT06600789 · Interventional

A Modular Phase 1/2 Study With CT7439 in Participants With Solid Malignancies

Solid Malignancies

Study overall: Recruiting · source record updated 3 September 2026.

3 England locations · 3 explicitly recorded as recruiting.

NCT06603844 · Interventional

First-in-human Study of CRB-601-01 to Treat Patients With Advanced Solid Tumor.

Solid Tumor

Study overall: Recruiting · source record updated 3 June 2025.

4 England locations · 0 explicitly recorded as recruiting.

NCT06609226 · Interventional

A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia

Sickle Cell Disease · Thalassemia

Study overall: Recruiting · source record updated 13 August 2026.

8 England locations · 6 explicitly recorded as recruiting.

NCT06615479 · Interventional

A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

Relapsed or Refractory Multiple Myeloma (RRMM)

Study overall: Recruiting · source record updated 18 August 2026.

6 England locations · 6 explicitly recorded as recruiting.

NCT06619587 · Interventional

A Study to Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors

Solid Tumor

Study overall: Recruiting · source record updated 25 August 2026.

3 England locations · 3 explicitly recorded as recruiting.

NCT06623422 · Interventional

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

Carcinoma, Non-Small-Cell Lung

Study overall: Recruiting · source record updated 27 August 2026.

12 England locations · 12 explicitly recorded as recruiting.

NCT06627647 · Interventional

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC

Non-squamous Non-small Cell Lung Cancer

Study overall: Recruiting · source record updated 14 August 2026.

8 England locations · 7 explicitly recorded as recruiting.

NCT06638541 · Interventional

Dose dE-eScalaTion IN prostATe radIOtherapy usiNg an MR-Linac in 2 Fractions

Prostate Cancer

Study overall: Recruiting · source record updated 23 March 2026.

2 England locations · 2 explicitly recorded as recruiting.

NCT06640959 · Observational

Chronic Radiation Induced Bowel Toxicity Study

Prostate Cancer

Study overall: Recruiting · source record updated 20 December 2024.

2 England locations · 2 explicitly recorded as recruiting.

NCT06644781 · Interventional

A Study of Ifinatamab Deruxtecan in Subjects With Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC) (IDeate-Esophageal01)

Esophageal Squamous Cell Carcinoma

Study overall: Recruiting · source record updated 4 August 2026.

6 England locations · 6 explicitly recorded as recruiting.

NCT06645236 · Interventional

DHF-20-1839-2: Clinical Performance Study Protocol for Therascreen® KRAS RGQ PCR Kit

Metastatic Colorectal Cancer (mCRC)

Study overall: Recruiting · source record updated 15 August 2025.

1 England locations · 1 explicitly recorded as recruiting.

NCT06646276 · Interventional

A Study to Compare the Efficacy and Safety of BMS-986489 (BMS-986012+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).

Extensive-Stage Small Cell Lung Cancer

Study overall: Recruiting · source record updated 31 August 2026.

3 England locations · 0 explicitly recorded as recruiting.

NCT06659341 · Interventional

A Phase I Study of BAY3498264 Given Together With Sotorasib in Participants Who Have Advanced Solid Cancers With Specific Genetic Changes Called KRASG12C Mutation

Advanced Solid Tumors Harboring KRAS G12C Mutation

Study overall: Recruiting · source record updated 26 August 2026.

2 England locations · 2 explicitly recorded as recruiting.

NCT06667076 · Interventional

A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Carcinoma, Non-Small-Cell Lung

Study overall: Recruiting · source record updated 28 August 2026.

6 England locations · 6 explicitly recorded as recruiting.

NCT06678841 · Interventional

ELEVATE-HFpEF Clinical Study

Heart Failure With Preserved Ejection Fraction (HFpEF)

Study overall: Recruiting · source record updated 3 August 2026.

3 England locations · 3 explicitly recorded as recruiting.

NCT06681545 · Observational

Exploring the Lived Experience of Young Adults With Severe Asthma

Asthma · Severe Asthma · Uncontrolled Asthma

Study overall: Recruiting · source record updated 5 February 2025.

1 England locations · 1 explicitly recorded as recruiting.

NCT06692738 · Interventional

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

Non-small Cell Lung Cancer

Study overall: Recruiting · source record updated 13 August 2026.

8 England locations · 7 explicitly recorded as recruiting.

NCT06695494 · Observational

Enabling Genomic Testing in Cancer of Unknown Primary

Cancer of Unknown Primary · Neoplasm, Unknown Primary

Study overall: Recruiting · source record updated 25 March 2026.

6 England locations · 6 explicitly recorded as recruiting.

NCT06712316 · Interventional

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

Non-small Cell Lung Cancer

Study overall: Recruiting · source record updated 4 September 2026.

15 England locations · 15 explicitly recorded as recruiting.

NCT06712355 · Interventional

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

Extensive-stage Small-cell Lung Cancer

Study overall: Recruiting · source record updated 1 September 2026.

16 England locations · 16 explicitly recorded as recruiting.

More ways to explore research

This is a selected international registry feed, not every study taking place in England. NIHR also lists participation opportunities, including studies that may not appear in this selection.

NIHR Be Part of Research Search the original register

Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).

Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.

How we selected and connected these records

Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.