NCT06317727 · Observational
PULSed Field ablAtion of coloRectal Polyps
Colon Polyp
Study overall: Recruiting · source record updated 3 March 2026.
1 England locations · 1 explicitly recorded as recruiting.
RESEARCH IN ENGLAND
Explore clinical trials with England locations
Search 2,970 registered studies with identifiable England locations in our dated ClinicalTrials.gov snapshot. Explore the study and local recruitment details before contacting the research team.
254 matching studies · ordered by study identifier.
The area filter uses exact source postcodes. Locations without a matched postcode remain in the England-wide results.
NCT06318169 · Interventional
A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis
Study overall: Recruiting · source record updated 3 September 2026.
15 England locations · 14 explicitly recorded as recruiting.
NCT06338995 · Interventional
A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)
Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Study overall: Recruiting · source record updated 8 September 2026.
7 England locations · 7 explicitly recorded as recruiting.
NCT06339580 · Interventional
Assessment of Volume-targeted Ventilation in Patients With Neuromuscular Disease
Neuromuscular Diseases
Study overall: Recruiting · source record updated 8 June 2026.
2 England locations · 2 explicitly recorded as recruiting.
NCT06355583 · Interventional
Intestinal Microbiota Transplant Prior to Allogeneic Stem Cell Transplant (MAST) Trial
Acute Lymphoblastic Leukaemia · Acute Leukemia of Ambiguous Lineage · Chronic Myeloid Leukemia · Chronic Myelomonocytic Leukemia · Myelodysplastic Syndrome · Acute Myeloid Leukemia
Study overall: Recruiting · source record updated 17 April 2025.
8 England locations · 6 explicitly recorded as recruiting.
NCT06379789 · Interventional
A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia B
Hemophilia B
Study overall: Recruiting · source record updated 5 August 2026.
6 England locations · 6 explicitly recorded as recruiting.
NCT06401356 · Interventional
An Extension Study for Patients Previously Enrolled in Studies With Pelabresib
Hematologic Malignancy · Solid Tumor · Advanced Malignancies
Study overall: Recruiting · source record updated 11 June 2026.
1 England locations · 1 explicitly recorded as recruiting.
NCT06419374 · Interventional
A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH
Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis
Study overall: Recruiting · source record updated 3 September 2026.
10 England locations · 10 explicitly recorded as recruiting.
NCT06449001 · Interventional
Study of Danicopan as Add-on Treatment to Ravulizumab or Eculizumab in Pediatric Participants With PNH Who Have Clinically Significant Extravascular Hemolysis
Paroxysmal Nocturnal Hemoglobinuria · PNH · Extravascular Hemolysis
Study overall: Recruiting · source record updated 23 December 2025.
2 England locations · 2 explicitly recorded as recruiting.
NCT06449079 · Observational
The PICM Risk Prediction Study - Application of AI to Pacing
Heart Failure · Pacemaker-Induced Cardiomyopathy · Pacemaker Complication
Study overall: Not yet recruiting · source record updated 7 June 2024.
3 England locations · 0 explicitly recorded as recruiting.
NCT06461208 · Interventional
A PROspective Faecal MIcrobiota tranSplantation Trial to Improve outcomEs in Patients With Cirrhosis
Liver Cirrhosis
Study overall: Recruiting · source record updated 24 February 2026.
17 England locations · 17 explicitly recorded as recruiting.
NCT06461897 · Interventional
A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis
Atopic Dermatitis
Study overall: Recruiting · source record updated 6 August 2026.
7 England locations · 6 explicitly recorded as recruiting.
NCT06464926 · Interventional
Chronic Nausea and Vomiting in Patients With Normal Gastric Emptying Using the Enterra® Therapy System (NAVIGATE)
Nausea · Vomiting
Study overall: Recruiting · source record updated 14 May 2026.
4 England locations · 4 explicitly recorded as recruiting.
NCT06468124 · Observational
Sensitivity of Organoids to Predict Treatment Outcome in Breast Cancer Metastases
Breast Neoplasms
Study overall: Recruiting · source record updated 22 December 2025.
2 England locations · 2 explicitly recorded as recruiting.
NCT06481306 · Interventional
A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease
Anemia, Sickle Cell · Healthy Volunteers
Study overall: Recruiting · source record updated 18 August 2026.
5 England locations · 2 explicitly recorded as recruiting.
NCT06499285 · Interventional
A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions
Myelodysplastic Syndromes
Study overall: Recruiting · source record updated 21 August 2026.
11 England locations · 9 explicitly recorded as recruiting.
NCT06526793 · Interventional
Surovatamig (AZD0486) as Monotherapy in Participants With Relapsed/Refractory (R/R) B-cell NHL
B-cell Non-Hodgkin Lymphoma · Follicular Lymphoma (FL) · Large B-Cell Lymphoma (LBCL)
Study overall: Recruiting · source record updated 13 August 2026.
5 England locations · 5 explicitly recorded as recruiting.
NCT06528314 · Interventional
A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH
NASH - Nonalcoholic Steatohepatitis · MASH - Metabolic Dysfunction-Associated Steatohepatitis
Study overall: Recruiting · source record updated 8 September 2026.
7 England locations · 7 explicitly recorded as recruiting.
NCT06531824 · Interventional
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)
Kidney Disease, Chronic
Study overall: Recruiting · source record updated 2 September 2026.
58 England locations · 58 explicitly recorded as recruiting.
NCT06537921 · Interventional
Comorbid Obesity and Depression With an Anti-inflammatory Medication
Obesity · Major Depressive Disorder · Inflammation
Study overall: Recruiting · source record updated 14 November 2025.
1 England locations · 1 explicitly recorded as recruiting.
More ways to explore research
This is a selected international registry feed, not every study taking place in England. NIHR also lists participation opportunities, including studies that may not appear in this selection.
Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).
Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.
How we selected and connected these records
Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.