RESEARCH IN ENGLAND

Explore clinical trials with England locations

Search 2,970 registered studies with identifiable England locations in our dated ClinicalTrials.gov snapshot. Explore the study and local recruitment details before contacting the research team.

Condition, study or locationRecorded care areaStatus at an England locationClear filters

230 matching studies · ordered by study identifier.

The area filter uses exact source postcodes. Locations without a matched postcode remain in the England-wide results.

NCT07008742 · Observational

Feasibility Study of Tissue and Blood Collection in Oncogene-addicted and Neoadjuvantly Treated Non Small Cell Lung Cancer

Oncogene-addicted Non Small Cell Lung Cancer · Early-stage Operable Non Small Cell Lung Cancer · Non Small Cell Lung Cancer · Metastatic Non Small Cell Lung Cancer · Locally Advanced NSCLC - Non-Small Cell Lung Cancer · Stage 2/3 Operable Non Small Cell Lung Cancer

Study overall: Recruiting · source record updated 15 June 2025.

1 England locations · 1 explicitly recorded as recruiting.

NCT07023614 · Interventional

A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy

Non-obstructive Hypertrophic Cardiomyopathy

Study overall: Recruiting · source record updated 18 May 2026.

4 England locations · 4 explicitly recorded as recruiting.

NCT07028853 · Interventional

This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.

Metastatic Castration Sensitive Prostate Cancer (mCSPC) · Hormone Sensitive Prostate Cancer · Prostate Cancer · Cancer of the Prostate

Study overall: Recruiting · source record updated 14 August 2026.

8 England locations · 8 explicitly recorded as recruiting.

NCT07037433 · Interventional

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

Atherosclerotic Cardiovascular Disease · Overweight · Obesity

Study overall: Recruiting · source record updated 3 September 2026.

24 England locations · 22 explicitly recorded as recruiting.

NCT07070232 · Interventional

A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors

Advanced Solid Tumor

Study overall: Recruiting · source record updated 2 September 2026.

10 England locations · 10 explicitly recorded as recruiting.

NCT07084571 · Observational

Feasibility of Serial Multisite Image-guided Biopsy to Study Breast Cancer Evolution

Breast Cancer · Metastatic Breast Cancer · Triple Negative Breast Cancer

Study overall: Recruiting · source record updated 12 March 2026.

1 England locations · 1 explicitly recorded as recruiting.

NCT07088068 · Interventional

A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes

Type 1 Diabetes Mellitus

Study overall: Recruiting · source record updated 9 September 2026.

9 England locations · 9 explicitly recorded as recruiting.

NCT07100080 · Interventional

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

Non-Small Cell Lung Cancer

Study overall: Recruiting · source record updated 25 August 2026.

3 England locations · 0 explicitly recorded as recruiting.

NCT07102433 · Observational

Complexity in Health, Education, and Social Support for Children and Young People With Life-limiting Conditions.

Complex Care · Medical Complexity · Pediatrics · Life-limiting Illness · Life-threatening Illness

Study overall: Recruiting · source record updated 5 August 2026.

5 England locations · 5 explicitly recorded as recruiting.

NCT07111520 · Interventional

A Clinical Trial to Test if an Investigational Combination Therapy With BNT326 and BNT327 is Safe and Potentially Beneficial for People With Advanced Non-small Cell Lung Cancer (NSCLC)

Non-small Cell Lung Cancer

Study overall: Recruiting · source record updated 5 August 2026.

4 England locations · 4 explicitly recorded as recruiting.

NCT07124390 · Interventional

Electroacupuncture as a Treatment for Refractory Overactive Bladder

Over Active Bladder · Urinary Incontinence (UI) · Nocturia

Study overall: Recruiting · source record updated 28 August 2026.

1 England locations · 1 explicitly recorded as recruiting.

NCT07167251 · Observational

Management of Immune Checkpoint Inhibition-related Hepatitis Using Low-dose Corticosteroids

Immune Related Adverse Events · Immune-Mediated Hepatitis · Cancer

Study overall: Recruiting · source record updated 11 September 2025.

1 England locations · 0 explicitly recorded as recruiting.

NCT07174336 · Interventional

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

Breast Neoplasms · Neoplasm Metastasis

Study overall: Recruiting · source record updated 8 September 2026.

7 England locations · 3 explicitly recorded as recruiting.

NCT07176689 · Interventional

Nirogacestat in Premenopausal Females With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)

Desmoid Tumor · Aggressive Fibromatosis

Study overall: Recruiting · source record updated 17 August 2026.

4 England locations · 4 explicitly recorded as recruiting.

NCT07185997 · Interventional

Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations

Non-Small-Cell Lung Cancer · Metastatic Non-Small-Cell Lung Cancer · Advanced Non-Small-Cell Lung Cancer · EGFR P-Loop and Alpha C-Helix Compressing · EGFR PACC · EGFR Uncommon Mutations

Study overall: Recruiting · source record updated 1 September 2026.

3 England locations · 3 explicitly recorded as recruiting.

NCT07189403 · Interventional

A Study of DS9051b in Participants With Advanced or Metastatic Adrenocortical Carcinoma and Metastatic Castration-resistant Prostate Cancer

Advanced or Metastatic Adrenocortical Carcinoma · Metastatic Castration-resistant Prostate Cancer

Study overall: Recruiting · source record updated 22 May 2026.

1 England locations · 0 explicitly recorded as recruiting.

NCT07195695 · Interventional

Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations

Non-small Cell Lung Cancer

Study overall: Recruiting · source record updated 3 September 2026.

4 England locations · 4 explicitly recorded as recruiting.

NCT07200908 · Interventional

A Trial Evaluating Brelovitug (BJT-778) vs Bulevirtide for the Treatment of Chronic Hepatitis Delta Infection (AZURE-2)

Chronic Hepatitis D Infection

Study overall: Recruiting · source record updated 25 August 2026.

6 England locations · 6 explicitly recorded as recruiting.

NCT07201922 · Interventional

A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary Fibrosis

Familial Pulmonary Fibrosis · Interstitial Lung Abnormalities · Interstitial Lung Diseases

Study overall: Recruiting · source record updated 8 September 2026.

2 England locations · 2 explicitly recorded as recruiting.

NCT07210723 · Interventional

A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy

Symptomatic Genetic Dilated Cardiomyopathy

Study overall: Recruiting · source record updated 4 August 2026.

7 England locations · 7 explicitly recorded as recruiting.

More ways to explore research

This is a selected international registry feed, not every study taking place in England. NIHR also lists participation opportunities, including studies that may not appear in this selection.

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Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).

Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.

How we selected and connected these records

Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.