NCT06507579 · Observational
Hydra Registry - UK
Aortic Valve Stenosis
Study overall: Recruiting · source record updated 18 August 2026.
3 England locations · 2 explicitly recorded as recruiting.
RESEARCH IN ENGLAND
Explore clinical trials with England locations
Search 2,970 registered studies with identifiable England locations in our dated ClinicalTrials.gov snapshot. Explore the study and local recruitment details before contacting the research team.
44 matching studies · ordered by study identifier.
The area filter uses exact source postcodes. Locations without a matched postcode remain in the England-wide results.
NCT06662786 · Interventional
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
Colorectal Neoplasms
Study overall: Recruiting · source record updated 28 August 2026.
8 England locations · 8 explicitly recorded as recruiting.
NCT06712316 · Interventional
Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer
Non-small Cell Lung Cancer
Study overall: Recruiting · source record updated 4 September 2026.
15 England locations · 15 explicitly recorded as recruiting.
NCT06712355 · Interventional
Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer
Extensive-stage Small-cell Lung Cancer
Study overall: Recruiting · source record updated 1 September 2026.
16 England locations · 16 explicitly recorded as recruiting.
NCT06736574 · Interventional
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
Heart Failure · Heart Failure With Reduced Ejection Fraction
Study overall: Recruiting · source record updated 28 August 2026.
6 England locations · 6 explicitly recorded as recruiting.
NCT06750094 · Interventional
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
Colorectal Neoplasms
Study overall: Recruiting · source record updated 28 August 2026.
7 England locations · 7 explicitly recorded as recruiting.
NCT06868277 · Interventional
A Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line Treatment of PD-L1-high Metastatic Non-small Cell Lung Cancer
Carcinoma, Non-Small Cell Lung
Study overall: Recruiting · source record updated 3 August 2026.
5 England locations · 5 explicitly recorded as recruiting.
NCT06883305 · Interventional
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
Chronic Obstructive Pulmonary Disease (COPD)
Study overall: Recruiting · source record updated 3 September 2026.
8 England locations · 8 explicitly recorded as recruiting.
NCT06919965 · Interventional
A Study to Evaluate TAR-210 Versus Intravesical Chemotherapy Treatment in Participants With High Risk Non-Muscle-Invasive Bladder Cancer
Non-Muscle Invasive Bladder Neoplasms
Study overall: Recruiting · source record updated 28 August 2026.
5 England locations · 5 explicitly recorded as recruiting.
NCT06951217 · Interventional
An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL)
Progressive Pulmonary Fibrosis · Idiopathic Pulmonary Fibrosis (IPF)
Study overall: Recruiting · source record updated 28 August 2026.
5 England locations · 5 explicitly recorded as recruiting.
NCT07067658 · Interventional
Monitoring Oedema in Heart Failure to Improve Function and Reduce Hospitalisation Risk
Heart Failure
Study overall: Recruiting · source record updated 28 July 2026.
14 England locations · 12 explicitly recorded as recruiting.
NCT07082738 · Interventional
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD)
Study overall: Recruiting · source record updated 9 September 2026.
8 England locations · 5 explicitly recorded as recruiting.
NCT07104565 · Interventional
Study to Assess the Safety and Tolerability of Tafasitamab in Adult Participants With Primary Autoimmune Blood Cell Disorders
Immune Thrombocytopenia
Study overall: Recruiting · source record updated 6 August 2026.
3 England locations · 3 explicitly recorded as recruiting.
NCT07173751 · Interventional
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
Breast Neoplasms
Study overall: Recruiting · source record updated 8 September 2026.
13 England locations · 13 explicitly recorded as recruiting.
NCT07200908 · Interventional
A Trial Evaluating Brelovitug (BJT-778) vs Bulevirtide for the Treatment of Chronic Hepatitis Delta Infection (AZURE-2)
Chronic Hepatitis D Infection
Study overall: Recruiting · source record updated 25 August 2026.
6 England locations · 6 explicitly recorded as recruiting.
NCT07218341 · Interventional
A Study of Pirtobrutinib (LY3527727) in Participants With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia · Lymphoma, Small Lymphocytic
Study overall: Recruiting · source record updated 4 September 2026.
3 England locations · 1 explicitly recorded as recruiting.
NCT07276399 · Interventional
A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer
Squamous Cell Carcinoma of Head and Neck
Study overall: Recruiting · source record updated 28 August 2026.
10 England locations · 10 explicitly recorded as recruiting.
NCT07281040 · Observational
Preparatory Work for a Trial of Adjuncts to Diuretic Treatment in Patients Hospitalised With Heart Failure: Addressing Uncertainties and Building Consensus
Heart Failure
Study overall: Recruiting · source record updated 15 December 2025.
1 England locations · 1 explicitly recorded as recruiting.
NCT07409519 · Observational
Nutritional Screening in Cardiovascular Disease
Cardiovascular Diseases
Study overall: Recruiting · source record updated 23 June 2026.
1 England locations · 1 explicitly recorded as recruiting.
NCT07441408 · Interventional
Long-term Extension Study to Evaluate Safety and Tolerability of Admilparant in Participants With Pulmonary Fibrosis
Pulmonary Fibrosis
Study overall: Not yet recruiting · source record updated 14 August 2026.
8 England locations · 0 explicitly recorded as recruiting.
More ways to explore research
This is a selected international registry feed, not every study taking place in England. NIHR also lists participation opportunities, including studies that may not appear in this selection.
Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).
Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.
How we selected and connected these records
Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.