RESEARCH IN ENGLAND

Explore clinical trials with England locations

Search 2,970 registered studies with identifiable England locations in our dated ClinicalTrials.gov snapshot. Explore the study and local recruitment details before contacting the research team.

Condition, study or locationRecorded care areaStatus at an England locationClear filters

77 matching studies · ordered by study identifier.

The area filter uses exact source postcodes. Locations without a matched postcode remain in the England-wide results.

NCT06149286 · Interventional

A Trial to Find Out if Odronextamab Combined With Lenalidomide is Safe and Works Better Than Rituximab Combined With Lenalidomide in Adult Participants With Follicular Lymphoma and Marginal Zone Lymphoma

Relapsed/Refractory Follicular Lymphoma · Relapsed/Refractory Marginal Zone Lymphoma (R/R MZL)

Study overall: Recruiting · source record updated 14 August 2026.

9 England locations · 9 explicitly recorded as recruiting.

NCT06283966 · Interventional

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

COPD (Chronic Obstructive Pulmonary Disease)

Study overall: Recruiting · source record updated 26 August 2026.

23 England locations · 13 explicitly recorded as recruiting.

NCT06312176 · Interventional

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

Breast Neoplasms

Study overall: Recruiting · source record updated 3 September 2026.

5 England locations · 5 explicitly recorded as recruiting.

NCT06340568 · Interventional

A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer

Endometrial Cancer

Study overall: Recruiting · source record updated 1 September 2026.

11 England locations · 11 explicitly recorded as recruiting.

NCT06357533 · Interventional

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

Non-Small Cell Lung Cancer

Study overall: Recruiting · source record updated 12 August 2026.

7 England locations · 4 explicitly recorded as recruiting.

NCT06380751 · Interventional

Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

Advanced Breast Cancer

Study overall: Recruiting · source record updated 2 September 2026.

7 England locations · 6 explicitly recorded as recruiting.

NCT06393374 · Interventional

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

Triple-Negative Breast Cancer

Study overall: Recruiting · source record updated 3 September 2026.

5 England locations · 5 explicitly recorded as recruiting.

NCT06424288 · Interventional

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

Heart Failure

Study overall: Recruiting · source record updated 21 August 2026.

10 England locations · 9 explicitly recorded as recruiting.

NCT06492616 · Interventional

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

Breast Cancer

Study overall: Recruiting · source record updated 17 August 2026.

14 England locations · 14 explicitly recorded as recruiting.

NCT06531824 · Interventional

EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)

Kidney Disease, Chronic

Study overall: Recruiting · source record updated 2 September 2026.

58 England locations · 58 explicitly recorded as recruiting.

NCT06544499 · Interventional

A Study to Assess the Efficacy and Safety of Efgartigimod IV in Adult Participants With Primary Immune Thrombocytopenia

Primary Immune Thrombocytopenia (ITP)

Study overall: Recruiting · source record updated 1 May 2026.

7 England locations · 7 explicitly recorded as recruiting.

NCT06605820 · Observational

Shared Decision-making and Antimicrobial Stewardship in Secondary Care

Antibiotic Prescribing is the Study Focus (no Condition)

Study overall: Recruiting · source record updated 4 June 2025.

2 England locations · 2 explicitly recorded as recruiting.

NCT06677060 · Interventional

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

Heart Failure

Study overall: Recruiting · source record updated 31 July 2026.

13 England locations · 9 explicitly recorded as recruiting.

NCT06745908 · Interventional

Clinical Trial of N-803 Plus Tislelizumab or Prior Failed Immune Checkpoint Inhibitor and Docetaxel Versus Docetaxel Monotherapy in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Acquired Resistance to Immune Checkpoint In

NSCLC Stage IV

Study overall: Recruiting · source record updated 27 July 2026.

5 England locations · 5 explicitly recorded as recruiting.

NCT06758401 · Interventional

This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.

Non-Small Cell Lung Cancer · Carcinoma, Non-Small-Cell Lung · Carcinoma, Non-Small-Cell Lung (NSCLC)

Study overall: Recruiting · source record updated 22 July 2026.

8 England locations · 4 explicitly recorded as recruiting.

NCT06806592 · Interventional

A Study to Test Whether Nerandomilast Helps People With Lungfibrosis Related to Rheumatic Diseases

Interstitial Lung Diseases · Systemic Autoimmune Rheumatic Diseases Associated Interstitial Lung Diseases

Study overall: Recruiting · source record updated 8 September 2026.

11 England locations · 3 explicitly recorded as recruiting.

NCT06830759 · Observational

Real-World Study to Assess Subcutaneous Epcoritamab in Adult Participants With Diffuse Large B-Cell and Follicular Lymphoma

Diffuse Large B-cell Lymphoma · Follicular Lymphoma

Study overall: Recruiting · source record updated 17 February 2026.

7 England locations · 7 explicitly recorded as recruiting.

NCT06841354 · Interventional

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

Triple Negative Breast Neoplasms

Study overall: Recruiting · source record updated 3 September 2026.

7 England locations · 7 explicitly recorded as recruiting.

NCT06849284 · Observational

To Perform a Post-market Study of the Performance of the Idylla ThyroidPrint Assay Using Clinical Samples in Predicting the Nature of Indeterminate Thyroid Nodules (ITNs) Across Multiple Centers.

Thyroid Cancer

Study overall: Recruiting · source record updated 4 June 2025.

1 England locations · 1 explicitly recorded as recruiting.

NCT06897475 · Interventional

A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

Type 2 Diabetes

Study overall: Recruiting · source record updated 21 August 2026.

10 England locations · 10 explicitly recorded as recruiting.

More ways to explore research

This is a selected international registry feed, not every study taking place in England. NIHR also lists participation opportunities, including studies that may not appear in this selection.

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Source: ClinicalTrials.gov, a United States Government database. Contains OS data © Crown copyright and database right 2026. Contains National Statistics data © Crown copyright and database right 2024; ONS country boundaries (December 2024).

Source processed: 2026-09-10 09:00:04 UTC. Retrieved: 10 September 2026. ClinicalTrials.gov terms.

How we selected and connected these records

Selected registered studies with an overall status of Recruiting or Not yet recruiting and at least one England location established by postcode, recorded nation, or source coordinates within the ONS December 2024 boundary. Retained structured fields; omitted descriptions, eligibility text, contacts and non-England locations. Deduplicated identical locations. Linked local care areas only by exact postcode geography. Location points are used for nation filtering, not directions or facility matching.